Controlled release of drugs in electrosprayed nanoparticles for bone tissue engineering

Generating porous topographic substrates, by mimicking the native extracellular matrix (ECM) to promote the regeneration of damaged bone tissues, is a challenging process. Generally, scaffolds developed for bone tissue regeneration support bone cell growth and induce bone-forming cells by natural pr...

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Veröffentlicht in:	Advanced drug delivery reviews 2015-11, Vol.94, p.77-95
Hauptverfasser:	Jayaraman, Praveena, Gandhimathi, Chinnasamy, Venugopal, Jayarama Reddy, Becker, David Laurence, Ramakrishna, Seeram, Srinivasan, Dinesh Kumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - administration & dosage Biocompatible Materials Bone Regeneration - drug effects Bone Regeneration - physiology Bone tissue engineering Delayed-Action Preparations Drug delivery systems Drug Delivery Systems - methods Electrospray Humans Mesenchymal Stromal Cells - metabolism Nanoparticles Nanoparticles - chemistry Osteoblasts - metabolism Particle Size Polymers - chemistry Porosity Regenerative medicine Surface Properties Technology, Pharmaceutical Tissue Engineering - methods Tissue Scaffolds
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