Effects of Interferon Beta, Cyclophosphamide and Azathioprine on Cytokine Profile in Patients with Multiple Sclerosis

We assessed the in vitro effects of interferon beta-1b (IFNβ-1b), cyclophosphamide (CY), and azathioprine (AZA) alone and of the combination of IFNβ-1b with CY or AZA on the production of Th1 and Th2 cytokines in 10 patients with multiple sclerosis. Cytokine levels were determined at baseline and af...

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Veröffentlicht in:	International journal of immunopathology and pharmacology 2005-04, Vol.18 (2), p.377-383
Hauptverfasser:	Totaro, R., Passacantando, A., Russo, T., Parzanese, I., Rascente, M., Marini, C., Tonietti, G., Carolei, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Azathioprine - administration & dosage Azathioprine - therapeutic use Cyclophosphamide - administration & dosage Cyclophosphamide - therapeutic use Cytokines - blood Drug Therapy, Combination Female Humans Interferon beta-1b Interferon-beta - administration & dosage Interferon-beta - therapeutic use Interleukin-10 - blood Interleukin-2 - blood Interleukin-4 - blood Male Multiple Sclerosis - drug therapy Multiple Sclerosis - immunology Treatment Outcome Tumor Necrosis Factor-alpha - metabolism
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