A recombinant varicella vaccine harboring a respiratory syncytial virus gene induces humoral immunity

Abstract The varicella-zoster virus (VZV) Oka vaccine strain (vOka) is highly efficient and causes few adverse events; therefore, it is used worldwide. We previously constructed recombinant vOka (rvOka) harboring the mumps virus gene. Immunizing guinea pigs with rvOka induced the production of neutr...

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Veröffentlicht in:	Vaccine 2015-11, Vol.33 (45), p.6085-6092
Hauptverfasser:	Murakami, Kouki, Matsuura, Masaaki, Ota, Megumi, Gomi, Yasuyuki, Yamanishi, Koichi, Mori, Yasuko
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Antibodies, Neutralizing - biosynthesis Antibodies, Neutralizing - immunology Antibodies, Viral - biosynthesis Antibodies, Viral - immunology Antigens Artificial chromosomes Chicken pox Chickenpox - immunology Chickenpox Vaccine - administration & dosage Chickenpox Vaccine - genetics Chickenpox Vaccine - immunology Cloning Drug dosages E coli Fibroblasts Gene expression Genome, Viral Genomes Growth hormones Guinea Pigs Herpesvirus 3, Human - immunology Immunity, Humoral Immunoglobulins Immunology Infections Mumps virus Next generation vaccine Plasmids Public health Respiratory syncytial virus Respiratory Syncytial Virus Infections - immunology Respiratory Syncytial Virus Infections - prevention & control Respiratory Syncytial Virus Infections - virology Respiratory Syncytial Virus Vaccines - administration & dosage Respiratory Syncytial Virus Vaccines - genetics Respiratory Syncytial Virus Vaccines - immunology Respiratory Syncytial Viruses - genetics Respiratory Syncytial Viruses - immunology RSV Vaccine Vaccines Vaccines, Attenuated - administration & dosage Vaccines, Attenuated - immunology Vaccines, Synthetic - administration & dosage Vaccines, Synthetic - immunology Varicella-zoster virus Viral Fusion Proteins - immunology Viruses VZV
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