The effects of dietary oxidized konjac glucomannan and its acidolysis products on the immune response, expression of immune related genes and disease resistance of Schizothorax prenanti

In the present study, KGM was degraded by H2O2 and HCl to obtain two products with different molecular weights: oxidized konjac glucomannan (OKGM, 4.7 × 105 Da) and low-molecular-weight oxidized konjac glucomannan (L-OKGM, 9.2 × 103 Da). The effects of the two OKGM products on IL-1β, TNF-α, and TLR2...

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Veröffentlicht in:	Fish & shellfish immunology 2015-08, Vol.45 (2), p.551-559
Hauptverfasser:	Zheng, Qiaoran, Wu, Yinglong, Xu, Huailiang, Yao, Yongfang, Xia, Xiaojie, Feng, Jiao, Tang, Haolan, Wang, Hongjie
Format:	Artikel
Sprache:	eng
Schlagworte:	Aeromonas hydrophila Animals Cyprinidae - blood Cyprinidae - genetics Cyprinidae - immunology Dietary Supplements Disease Resistance - drug effects Fish Diseases - immunology Gene Expression Gram-Negative Bacterial Infections - immunology Head Kidney - metabolism Immunity Interleukin-1beta - genetics Interleukin-1β Intestines - metabolism Malondialdehyde - blood Mannans - chemistry Mannans - pharmacology Molecular weight Muramidase - blood Oxidized konjac glucomannan RNA, Messenger - metabolism Schizothorax Spleen - metabolism Superoxide Dismutase - metabolism Toll-like receptor 22 Toll-Like Receptors - genetics Tumor Necrosis Factor-alpha - genetics Tumor necrosis factor-α
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