Herd immunity and fatal cases of influenza among the population exposed to poultry and wild birds in Russian Asia in 2013-2014
In total 1,525 blood serum samples were collected in October, 2013 in Russian Asia from people who reside in territories that are at high risk for emergence of influenza viruses with pandemic potential. Presence of antibodies to influenza viruses in the sera was tested in hemagglutination inhibition...
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| Veröffentlicht in: | Journal of medical virology 2016-01, Vol.88 (1), p.35-44 |
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| creator | Ilyicheva, Tatyana Abdurashitov, Murat Durymanov, Alexander Susloparov, Ivan Goncharova, Natalya Kolosova, Natalya Mikheev, Valery Ryzhikov, Alexander |
| description | In total 1,525 blood serum samples were collected in October, 2013 in Russian Asia from people who reside in territories that are at high risk for emergence of influenza viruses with pandemic potential. Presence of antibodies to influenza viruses in the sera was tested in hemagglutination inhibition test. None of the samples produced positive results with the antigens A/H5 and A/H7. Twelve strains of influenza A(H1N1pdm09) virus were isolated from people who died presumably from influenza during 2013–2014 epidemic season. All strains were similar to vaccine strain A/California/07/09 according to their antigenic properties and sensitivity to anti‐neuraminidase drugs (oseltamivir and zanamivir). Genetic analysis revealed that all strains belong to group 6, subgroup 6B of influenza A(H1N1)pdm09 virus. Substitutions in HA1: S164F add E235K as well as E47G, A86V, K331R, N386K, N397K in NA, and K131E, N29S in NS1, and N29S, R34Q in NEP separate investigated strains into two groups: 1st group—A/Chita/1114/2014, A/Chita/1115/2014, A/Chita/853/2014, A/Barnaul/269/2014 and 2nd group—A/Chita/655/2014, A/Chita/656/2014, A/Chita/709/2014, A/Chita/873/2014. Mutation D222G in HA1, which is often associated with high morbidity of the illness, was present in strain A/Novosibirsk/114/2014. Substitution N386K in NA removes a potential N‐glycosylation site in neuraminidases of A/Chita/1114/2014, A/Chita/1115/2014, A/Chita/853/2014, A/Barnaul/269/2014, A/Novosibirsk/114/2014, and A/Blagoveshensk/252/2014. J. Med. Virol. 88:35–44, 2016. © 2015 Wiley Periodicals, Inc. |
| doi_str_mv | 10.1002/jmv.24301 |
| format | Article |
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Presence of antibodies to influenza viruses in the sera was tested in hemagglutination inhibition test. None of the samples produced positive results with the antigens A/H5 and A/H7. Twelve strains of influenza A(H1N1pdm09) virus were isolated from people who died presumably from influenza during 2013–2014 epidemic season. All strains were similar to vaccine strain A/California/07/09 according to their antigenic properties and sensitivity to anti‐neuraminidase drugs (oseltamivir and zanamivir). Genetic analysis revealed that all strains belong to group 6, subgroup 6B of influenza A(H1N1)pdm09 virus. Substitutions in HA1: S164F add E235K as well as E47G, A86V, K331R, N386K, N397K in NA, and K131E, N29S in NS1, and N29S, R34Q in NEP separate investigated strains into two groups: 1st group—A/Chita/1114/2014, A/Chita/1115/2014, A/Chita/853/2014, A/Barnaul/269/2014 and 2nd group—A/Chita/655/2014, A/Chita/656/2014, A/Chita/709/2014, A/Chita/873/2014. Mutation D222G in HA1, which is often associated with high morbidity of the illness, was present in strain A/Novosibirsk/114/2014. Substitution N386K in NA removes a potential N‐glycosylation site in neuraminidases of A/Chita/1114/2014, A/Chita/1115/2014, A/Chita/853/2014, A/Barnaul/269/2014, A/Novosibirsk/114/2014, and A/Blagoveshensk/252/2014. J. Med. Virol. 88:35–44, 2016. © 2015 Wiley Periodicals, Inc.</description><identifier>ISSN: 0146-6615</identifier><identifier>EISSN: 1096-9071</identifier><identifier>DOI: 10.1002/jmv.24301</identifier><identifier>PMID: 26105790</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Amino Acid Substitution ; Animals ; Antibodies, Viral - blood ; Birds ; Child ; Child, Preschool ; Environmental Exposure ; Epidemiology ; Female ; Genotype ; Hemagglutination Inhibition Tests ; Hemagglutinin Glycoproteins, Influenza Virus - genetics ; human immunity ; Humans ; Immunity, Herd ; Infant ; Infant, Newborn ; Influenza ; Influenza A Virus, H1N1 Subtype - classification ; Influenza A Virus, H1N1 Subtype - genetics ; Influenza A Virus, H1N1 Subtype - isolation & purification ; influenza viruses ; Influenza, Human - immunology ; Influenza, Human - mortality ; Male ; Middle Aged ; Mutation, Missense ; phylogenic analysis ; Poultry ; sequencing ; Siberia - epidemiology ; Virology ; Young Adult</subject><ispartof>Journal of medical virology, 2016-01, Vol.88 (1), p.35-44</ispartof><rights>2015 Wiley Periodicals, Inc.</rights><rights>2016 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4941-f5603713609557f1463e3aeb2cdcac37c360fa998f96b52cbbd4fa6567aac00f3</citedby><cites>FETCH-LOGICAL-c4941-f5603713609557f1463e3aeb2cdcac37c360fa998f96b52cbbd4fa6567aac00f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjmv.24301$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjmv.24301$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26105790$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ilyicheva, Tatyana</creatorcontrib><creatorcontrib>Abdurashitov, Murat</creatorcontrib><creatorcontrib>Durymanov, Alexander</creatorcontrib><creatorcontrib>Susloparov, Ivan</creatorcontrib><creatorcontrib>Goncharova, Natalya</creatorcontrib><creatorcontrib>Kolosova, Natalya</creatorcontrib><creatorcontrib>Mikheev, Valery</creatorcontrib><creatorcontrib>Ryzhikov, Alexander</creatorcontrib><title>Herd immunity and fatal cases of influenza among the population exposed to poultry and wild birds in Russian Asia in 2013-2014</title><title>Journal of medical virology</title><addtitle>J. Med. Virol</addtitle><description>In total 1,525 blood serum samples were collected in October, 2013 in Russian Asia from people who reside in territories that are at high risk for emergence of influenza viruses with pandemic potential. Presence of antibodies to influenza viruses in the sera was tested in hemagglutination inhibition test. None of the samples produced positive results with the antigens A/H5 and A/H7. Twelve strains of influenza A(H1N1pdm09) virus were isolated from people who died presumably from influenza during 2013–2014 epidemic season. All strains were similar to vaccine strain A/California/07/09 according to their antigenic properties and sensitivity to anti‐neuraminidase drugs (oseltamivir and zanamivir). Genetic analysis revealed that all strains belong to group 6, subgroup 6B of influenza A(H1N1)pdm09 virus. Substitutions in HA1: S164F add E235K as well as E47G, A86V, K331R, N386K, N397K in NA, and K131E, N29S in NS1, and N29S, R34Q in NEP separate investigated strains into two groups: 1st group—A/Chita/1114/2014, A/Chita/1115/2014, A/Chita/853/2014, A/Barnaul/269/2014 and 2nd group—A/Chita/655/2014, A/Chita/656/2014, A/Chita/709/2014, A/Chita/873/2014. Mutation D222G in HA1, which is often associated with high morbidity of the illness, was present in strain A/Novosibirsk/114/2014. Substitution N386K in NA removes a potential N‐glycosylation site in neuraminidases of A/Chita/1114/2014, A/Chita/1115/2014, A/Chita/853/2014, A/Barnaul/269/2014, A/Novosibirsk/114/2014, and A/Blagoveshensk/252/2014. J. Med. Virol. 88:35–44, 2016. © 2015 Wiley Periodicals, Inc.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Amino Acid Substitution</subject><subject>Animals</subject><subject>Antibodies, Viral - blood</subject><subject>Birds</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Environmental Exposure</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Genotype</subject><subject>Hemagglutination Inhibition Tests</subject><subject>Hemagglutinin Glycoproteins, Influenza Virus - genetics</subject><subject>human immunity</subject><subject>Humans</subject><subject>Immunity, Herd</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Influenza</subject><subject>Influenza A Virus, H1N1 Subtype - classification</subject><subject>Influenza A Virus, H1N1 Subtype - genetics</subject><subject>Influenza A Virus, H1N1 Subtype - isolation & purification</subject><subject>influenza viruses</subject><subject>Influenza, Human - immunology</subject><subject>Influenza, Human - mortality</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mutation, Missense</subject><subject>phylogenic analysis</subject><subject>Poultry</subject><subject>sequencing</subject><subject>Siberia - epidemiology</subject><subject>Virology</subject><subject>Young Adult</subject><issn>0146-6615</issn><issn>1096-9071</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkcFu1DAQhi0EokvhwAsgS1zoIe3Yju3kWC10CyogEBSJi-U4NnhJ4mAn0OXAs-M2bQ9ISFzG8vibTxr_CD0mcEgA6NG2_3FISwbkDloRqEVRgyR30QpIKQohCN9DD1LaAkBVU3of7VFBgMsaVuj3qY0t9n0_D37aYT202OlJd9joZBMODvvBdbMdfmms-zB8wdNXi8cwzp2efBiwvRhDsi2eQu7O3RQXyU_ftbjxsU1ZgN_PKXk94ONcL-8UCCtyKR-ie053yT66PvfRx5MXH9anxdnbzcv18VlhyrokheMCmCRMQM25dHktZpm2DTWt0YZJk1-cruvK1aLh1DRNWzotuJBaGwDH9tGzxTvG8H22aVK9T8Z2nR5smJMikvGaCFZV_4HSSkhKWJnRp3-h2zDHIS9yRQEnVcUzdbBQJoaUonVqjL7XcacIqMv8VM5PXeWX2SfXxrnpbXtL3gSWgaMFyB9sd_82qVevz2-UxTLh02Qvbid0_KaEZJKrT282Cs7pevPu-WdVsj_ZvrG-</recordid><startdate>201601</startdate><enddate>201601</enddate><creator>Ilyicheva, Tatyana</creator><creator>Abdurashitov, Murat</creator><creator>Durymanov, Alexander</creator><creator>Susloparov, Ivan</creator><creator>Goncharova, Natalya</creator><creator>Kolosova, Natalya</creator><creator>Mikheev, Valery</creator><creator>Ryzhikov, Alexander</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7TK</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>7T2</scope><scope>7U2</scope></search><sort><creationdate>201601</creationdate><title>Herd immunity and fatal cases of influenza among the population exposed to poultry and wild birds in Russian Asia in 2013-2014</title><author>Ilyicheva, Tatyana ; 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Med. Virol</addtitle><date>2016-01</date><risdate>2016</risdate><volume>88</volume><issue>1</issue><spage>35</spage><epage>44</epage><pages>35-44</pages><issn>0146-6615</issn><eissn>1096-9071</eissn><abstract>In total 1,525 blood serum samples were collected in October, 2013 in Russian Asia from people who reside in territories that are at high risk for emergence of influenza viruses with pandemic potential. Presence of antibodies to influenza viruses in the sera was tested in hemagglutination inhibition test. None of the samples produced positive results with the antigens A/H5 and A/H7. Twelve strains of influenza A(H1N1pdm09) virus were isolated from people who died presumably from influenza during 2013–2014 epidemic season. All strains were similar to vaccine strain A/California/07/09 according to their antigenic properties and sensitivity to anti‐neuraminidase drugs (oseltamivir and zanamivir). Genetic analysis revealed that all strains belong to group 6, subgroup 6B of influenza A(H1N1)pdm09 virus. Substitutions in HA1: S164F add E235K as well as E47G, A86V, K331R, N386K, N397K in NA, and K131E, N29S in NS1, and N29S, R34Q in NEP separate investigated strains into two groups: 1st group—A/Chita/1114/2014, A/Chita/1115/2014, A/Chita/853/2014, A/Barnaul/269/2014 and 2nd group—A/Chita/655/2014, A/Chita/656/2014, A/Chita/709/2014, A/Chita/873/2014. Mutation D222G in HA1, which is often associated with high morbidity of the illness, was present in strain A/Novosibirsk/114/2014. Substitution N386K in NA removes a potential N‐glycosylation site in neuraminidases of A/Chita/1114/2014, A/Chita/1115/2014, A/Chita/853/2014, A/Barnaul/269/2014, A/Novosibirsk/114/2014, and A/Blagoveshensk/252/2014. J. Med. Virol. 88:35–44, 2016. © 2015 Wiley Periodicals, Inc.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>26105790</pmid><doi>10.1002/jmv.24301</doi><tpages>10</tpages></addata></record> |
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| subjects | Adolescent Adult Aged Aged, 80 and over Amino Acid Substitution Animals Antibodies, Viral - blood Birds Child Child, Preschool Environmental Exposure Epidemiology Female Genotype Hemagglutination Inhibition Tests Hemagglutinin Glycoproteins, Influenza Virus - genetics human immunity Humans Immunity, Herd Infant Infant, Newborn Influenza Influenza A Virus, H1N1 Subtype - classification Influenza A Virus, H1N1 Subtype - genetics Influenza A Virus, H1N1 Subtype - isolation & purification influenza viruses Influenza, Human - immunology Influenza, Human - mortality Male Middle Aged Mutation, Missense phylogenic analysis Poultry sequencing Siberia - epidemiology Virology Young Adult |
| title | Herd immunity and fatal cases of influenza among the population exposed to poultry and wild birds in Russian Asia in 2013-2014 |
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