In vitro genotoxicity testing of carvacrol and thymol using the micronucleus and mouse lymphoma assays

•Interest of carvacrol and thymol for the development of new active packaging•Carvacrol induces micronucleus at the highest concentration assayed in L5178Y cells•MLA assay did not show genotoxic response by any of both compounds Currently, antimicrobial additives derived from essential oils (Eos) ex...

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Veröffentlicht in:	Mutation research. Genetic toxicology and environmental mutagenesis 2015-06, Vol.784-785, p.37-44
Hauptverfasser:	Maisanaba, Sara, Prieto, Ana I., Puerto, Maria, Gutiérrez-Praena, Daniel, Demir, Eşref, Marcos, Ricard, Cameán, Ana M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioassays Carvacrol Cell Line, Tumor DNA Damage DNA, Neoplasm - drug effects Dose-Response Relationship, Drug Food additives Food Additives - toxicity Food packaging In Vitro Techniques Leukemia L5178 Lymphoma Mice Micronucleus test Micronucleus Tests Monoterpenes - toxicity Mouse lymphoma assay Mutation Oils & fats Origanum vulgare Thymol Thymol - toxicity Toxicology
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