Role of stem cells in spondyloarthritis: Pathogenesis, treatment and complications
Abstract Spondyloarthritis (SpA) is a family of interrelated inflammatory arthritis that includes ankylosing spondylitis (AS), psoriatic arthritis, reactive arthritis, arthritis related to inflammatory bowel disease and undifferentiated SpA. The classification, epidemiology, pathogenesis and treatme...
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| Veröffentlicht in: | Human immunology 2015-10, Vol.76 (10), p.781-788 |
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| creator | Wong, Rebecca S.Y |
| description | Abstract Spondyloarthritis (SpA) is a family of interrelated inflammatory arthritis that includes ankylosing spondylitis (AS), psoriatic arthritis, reactive arthritis, arthritis related to inflammatory bowel disease and undifferentiated SpA. The classification, epidemiology, pathogenesis and treatment of SpA have been extensively reviewed in the published literature. Reviews on the use of stem cells in various autoimmune diseases in general are also common. However, a review on the role of stem cells in SpA is currently lacking. This review focuses on the involvement of stem cells in the pathogenesis of SpA and the application of different types of stem cells in the treatment of SpA. It also addresses some of the complications which may arise as a result of the use of stem cells in the treatment of SpA. |
| doi_str_mv | 10.1016/j.humimm.2015.09.038 |
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The classification, epidemiology, pathogenesis and treatment of SpA have been extensively reviewed in the published literature. Reviews on the use of stem cells in various autoimmune diseases in general are also common. However, a review on the role of stem cells in SpA is currently lacking. This review focuses on the involvement of stem cells in the pathogenesis of SpA and the application of different types of stem cells in the treatment of SpA. 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therapy</subject><subject>Mesenchymal Stromal Cells - drug effects</subject><subject>Mesenchymal Stromal Cells - immunology</subject><subject>Mesenchymal Stromal Cells - pathology</subject><subject>Myeloablative Agonists - therapeutic use</subject><subject>Osteoblasts - drug effects</subject><subject>Osteoblasts - immunology</subject><subject>Osteoblasts - pathology</subject><subject>Pathogenesis</subject><subject>Severity of Illness Index</subject><subject>Spondylarthritis - immunology</subject><subject>Spondylarthritis - pathology</subject><subject>Spondylarthritis - therapy</subject><subject>Spondyloarthritis</subject><subject>Stem cells</subject><subject>Treatment</subject><issn>0198-8859</issn><issn>1879-1166</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU2LFDEQhoMo7rj6D0Ry9GC3lf6OB2FZ_IIFZdVzSCcVJ2MnGZO0MP_eNLN68KKnujxvFfW8hDxlUDNgw8tDvV-dda5ugPU18Bra6R7ZsWnkFWPDcJ_sgPGpmqaeX5BHKR0AYISxe0gumqFreNuMO3J7GxakwdCU0VGFy5Ko9TQdg9enJciY99Fmm17RTzLvwzf0mGx6QXNEmR36TKXXVAV3XKyS2QafHpMHRi4Jn9zNS_L17Zsv1--rm4_vPlxf3VSq6yFXjDNljJy1maFrFBitzDRL6IwyyDjXc9sYrkfQA7TtJFHPSsI4I-81zqZrL8nz895jDD9WTFk4m7YPpMewJsHGtues48D-Ay06CtkMBe3OqIohpYhGHKN1Mp4EA7GJFwdxFi828QK4KOJL7NndhXV2qP-EfpsuwOszgEXJT4tRJGXRK9Q2ospCB_uvC38vUIv1RfryHU-YDmGNvugWTKRGgPi8lb91z3qAbux5-wu5962O</recordid><startdate>20151001</startdate><enddate>20151001</enddate><creator>Wong, Rebecca S.Y</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QO</scope><scope>7T5</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope></search><sort><creationdate>20151001</creationdate><title>Role of stem cells in spondyloarthritis: Pathogenesis, treatment and complications</title><author>Wong, Rebecca S.Y</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c450t-191cffabdfb042c0fdcf8ba04fcfe199db32f9d70d60338aedbca07be95debf43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adipocytes - 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| fulltext | fulltext |
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| ispartof | Human immunology, 2015-10, Vol.76 (10), p.781-788 |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Adipocytes - drug effects Adipocytes - immunology Adipocytes - pathology Allergy and Immunology Antirheumatic Agents - therapeutic use Bone Marrow Transplantation - adverse effects Bone Marrow Transplantation - methods Cell Differentiation Cell Proliferation Clinical Trials as Topic Complications Cytokines - biosynthesis Cytokines - immunology Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cell Transplantation - methods Humans Inflammatory Bowel Diseases - immunology Inflammatory Bowel Diseases - pathology Inflammatory Bowel Diseases - therapy Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - immunology Mesenchymal Stromal Cells - pathology Myeloablative Agonists - therapeutic use Osteoblasts - drug effects Osteoblasts - immunology Osteoblasts - pathology Pathogenesis Severity of Illness Index Spondylarthritis - immunology Spondylarthritis - pathology Spondylarthritis - therapy Spondyloarthritis Stem cells Treatment |
| title | Role of stem cells in spondyloarthritis: Pathogenesis, treatment and complications |
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