Gadolinium(III)-Chelated Silica Nanospheres Integrating Chemotherapy and Photothermal Therapy for Cancer Treatment and Magnetic Resonance Imaging

The combination of therapy and diagnosis has been emerging as a promising strategy for cancer treatment. To realize chemotherapy, photothermal therapy, and magnetic resonance imaging (MRI) in one system, we have synthesized a new magnetic nanoparticle (Gd@SiO2-DOX/ICG-PDC) integrating doxorubicin (D...

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Veröffentlicht in:	ACS applied materials & interfaces 2015-11, Vol.7 (45), p.25014-25023
Hauptverfasser:	Cao, Mingjing, Wang, Pengyang, Kou, Yu, Wang, Jing, Liu, Jing, Li, Yanhui, Li, Jiayang, Wang, Liming, Chen, Chunying
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Cell Death - drug effects Chelating Agents - chemistry Endocytosis - drug effects Gadolinium - chemistry Humans Hyperthermia, Induced Infrared Rays Ions Magnetic Resonance Imaging MCF-7 Cells Nanospheres - chemistry Nanospheres - ultrastructure Neoplasms - drug therapy Phototherapy Silicon Dioxide - chemistry Spectrophotometry, Ultraviolet Temperature X-Ray Absorption Spectroscopy
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