Efficacy of orally administered Silexan in patients with anxiety-related restlessness and disturbed sleep – A randomized, placebo-controlled trial

Abstract The anxiolytic effect of Silexan, a patented active substance with an essential oil produced from Lavandula angustifolia flowers, was investigated in patients with anxiety-related restlessness and disturbed sleep. 170 out-patients with a diagnosis of restlessness (ICD-10 R45.1), a Hamilton...

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Veröffentlicht in:	European neuropsychopharmacology 2015-11, Vol.25 (11), p.1960-1967
Hauptverfasser:	Kasper, Siegfried, Anghelescu, Ion, Dienel, Angelika
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Aged Anti-Anxiety Agents - administration & dosage Anti-Anxiety Agents - adverse effects Anxiety Anxiety Disorders - complications Anxiety Disorders - drug therapy Anxiety Disorders - physiopathology Clinical trial Double-Blind Method Female Humans Internal Medicine Lavender Male Middle Aged Oils, Volatile - administration & dosage Oils, Volatile - adverse effects Patient Compliance Plant Oils - administration & dosage Plant Oils - adverse effects Psychiatric Status Rating Scales Psychiatry Psychomotor Agitation - drug therapy Psychomotor Agitation - etiology Psychomotor Agitation - physiopathology Restlessness Severity of Illness Index Silexan Sleep - drug effects Sleep Aids, Pharmaceutical - administration & dosage Sleep Aids, Pharmaceutical - adverse effects Sleep Wake Disorders - drug therapy Sleep Wake Disorders - etiology Sleep Wake Disorders - physiopathology Treatment efficacy Treatment Outcome Young Adult
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