A Low-Cost and High-Resolution Droplet Position Detector for an Intelligent Electrowetting on Dielectric Device
A low-cost and high-resolution capacitive-to-digital converter integrated circuit is used for droplet position detection in a digital microfluidic system. A field-programmable gate array FPGA is used as the integrated logic hub of the system for a highly reliable and efficient control of the circuit...
Gespeichert in:
| Veröffentlicht in: | Journal of Laboratory Automation 2015-12, Vol.20 (6), p.663-669 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 669 |
|---|---|
| container_issue | 6 |
| container_start_page | 663 |
| container_title | Journal of Laboratory Automation |
| container_volume | 20 |
| creator | Li, Yiyan Li, Hongzhong Baker, R. Jacob |
| description | A low-cost and high-resolution capacitive-to-digital converter integrated circuit is used for droplet position detection in a digital microfluidic system. A field-programmable gate array FPGA is used as the integrated logic hub of the system for a highly reliable and efficient control of the circuit. A fast-fabricating PCB (printed circuit board) substrate microfluidic system is proposed. Smaller actuation threshold voltages than those previously reported are obtained. Droplets (3 µL) are actuated by using a 200 V, 500 Hz modulating pulsed voltage. Droplet positions can be detected and displayed on a PC-based 3D animation in real time. The actuators and the capacitance sensing circuits are implemented on one PCB to reduce the size of the system. With the capacitive droplet position detection system, the PCB-based electrowetting on dielectric device (EWOD) reported in this work has promise in automating immunohistochemistry experiments. |
| doi_str_mv | 10.1177/2211068214566940 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1735331235</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_2211068214566940</sage_id><sourcerecordid>1735331235</sourcerecordid><originalsourceid>FETCH-LOGICAL-c445t-d40f1c4dbeda2439641759363347df8fe9d61c155498aa47adb140c2c7bee1563</originalsourceid><addsrcrecordid>eNp1UM9LwzAUDqK4MXf3JDl6qSZpkq7HMacbDBTRc0nT15rRNTNJHf73Zm56EHzwXuB9P8j7ELqk5IbSLLtljFIiJ4xyIWXOyQkaUsFJwrhgp2i4h5M9PkBj79cklswzlpNzNGBCkpwJMUR2ild2l8ysD1h1FV6Y5i15Bm_bPhjb4Ttnty0E_GS9OSwggA7W4Tq26vCyC9C2poEu4HkbIWd3EILpGrxnG_jeGR2FH0bDBTqrVethfHxH6PV-_jJbJKvHh-Vsuko05yIkFSc11bwqoVKMp7nkNBN5KtOUZ1U9qSGvJNVUCJ5PlOKZqkrKiWY6KwGokOkIXR98t86-9-BDsTFex5-qDmzvC5qlIk0pi3OEyIGqnfXeQV1sndko91lQUuyTLv4mHSVXR_e-3ED1K_jJNRKSA8GrBoq17V0Xr_3f8AufhoVz</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1735331235</pqid></control><display><type>article</type><title>A Low-Cost and High-Resolution Droplet Position Detector for an Intelligent Electrowetting on Dielectric Device</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Li, Yiyan ; Li, Hongzhong ; Baker, R. Jacob</creator><creatorcontrib>Li, Yiyan ; Li, Hongzhong ; Baker, R. Jacob</creatorcontrib><description>A low-cost and high-resolution capacitive-to-digital converter integrated circuit is used for droplet position detection in a digital microfluidic system. A field-programmable gate array FPGA is used as the integrated logic hub of the system for a highly reliable and efficient control of the circuit. A fast-fabricating PCB (printed circuit board) substrate microfluidic system is proposed. Smaller actuation threshold voltages than those previously reported are obtained. Droplets (3 µL) are actuated by using a 200 V, 500 Hz modulating pulsed voltage. Droplet positions can be detected and displayed on a PC-based 3D animation in real time. The actuators and the capacitance sensing circuits are implemented on one PCB to reduce the size of the system. With the capacitive droplet position detection system, the PCB-based electrowetting on dielectric device (EWOD) reported in this work has promise in automating immunohistochemistry experiments.</description><identifier>ISSN: 2211-0682</identifier><identifier>ISSN: 2472-6303</identifier><identifier>EISSN: 1540-2452</identifier><identifier>EISSN: 2211-0690</identifier><identifier>DOI: 10.1177/2211068214566940</identifier><identifier>PMID: 25609255</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Automation, Laboratory - economics ; Automation, Laboratory - methods ; Costs and Cost Analysis ; Electric Capacitance ; Electrowetting - economics ; Electrowetting - instrumentation ; Electrowetting - methods ; Microfluidics - economics ; Microfluidics - instrumentation ; Microfluidics - methods</subject><ispartof>Journal of Laboratory Automation, 2015-12, Vol.20 (6), p.663-669</ispartof><rights>2015 Society for Laboratory Automation and Screening</rights><rights>2015 Society for Laboratory Automation and Screening.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c445t-d40f1c4dbeda2439641759363347df8fe9d61c155498aa47adb140c2c7bee1563</citedby><cites>FETCH-LOGICAL-c445t-d40f1c4dbeda2439641759363347df8fe9d61c155498aa47adb140c2c7bee1563</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25609255$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Yiyan</creatorcontrib><creatorcontrib>Li, Hongzhong</creatorcontrib><creatorcontrib>Baker, R. Jacob</creatorcontrib><title>A Low-Cost and High-Resolution Droplet Position Detector for an Intelligent Electrowetting on Dielectric Device</title><title>Journal of Laboratory Automation</title><addtitle>J Lab Autom</addtitle><description>A low-cost and high-resolution capacitive-to-digital converter integrated circuit is used for droplet position detection in a digital microfluidic system. A field-programmable gate array FPGA is used as the integrated logic hub of the system for a highly reliable and efficient control of the circuit. A fast-fabricating PCB (printed circuit board) substrate microfluidic system is proposed. Smaller actuation threshold voltages than those previously reported are obtained. Droplets (3 µL) are actuated by using a 200 V, 500 Hz modulating pulsed voltage. Droplet positions can be detected and displayed on a PC-based 3D animation in real time. The actuators and the capacitance sensing circuits are implemented on one PCB to reduce the size of the system. With the capacitive droplet position detection system, the PCB-based electrowetting on dielectric device (EWOD) reported in this work has promise in automating immunohistochemistry experiments.</description><subject>Automation, Laboratory - economics</subject><subject>Automation, Laboratory - methods</subject><subject>Costs and Cost Analysis</subject><subject>Electric Capacitance</subject><subject>Electrowetting - economics</subject><subject>Electrowetting - instrumentation</subject><subject>Electrowetting - methods</subject><subject>Microfluidics - economics</subject><subject>Microfluidics - instrumentation</subject><subject>Microfluidics - methods</subject><issn>2211-0682</issn><issn>2472-6303</issn><issn>1540-2452</issn><issn>2211-0690</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1UM9LwzAUDqK4MXf3JDl6qSZpkq7HMacbDBTRc0nT15rRNTNJHf73Zm56EHzwXuB9P8j7ELqk5IbSLLtljFIiJ4xyIWXOyQkaUsFJwrhgp2i4h5M9PkBj79cklswzlpNzNGBCkpwJMUR2ild2l8ysD1h1FV6Y5i15Bm_bPhjb4Ttnty0E_GS9OSwggA7W4Tq26vCyC9C2poEu4HkbIWd3EILpGrxnG_jeGR2FH0bDBTqrVethfHxH6PV-_jJbJKvHh-Vsuko05yIkFSc11bwqoVKMp7nkNBN5KtOUZ1U9qSGvJNVUCJ5PlOKZqkrKiWY6KwGokOkIXR98t86-9-BDsTFex5-qDmzvC5qlIk0pi3OEyIGqnfXeQV1sndko91lQUuyTLv4mHSVXR_e-3ED1K_jJNRKSA8GrBoq17V0Xr_3f8AufhoVz</recordid><startdate>201512</startdate><enddate>201512</enddate><creator>Li, Yiyan</creator><creator>Li, Hongzhong</creator><creator>Baker, R. Jacob</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201512</creationdate><title>A Low-Cost and High-Resolution Droplet Position Detector for an Intelligent Electrowetting on Dielectric Device</title><author>Li, Yiyan ; Li, Hongzhong ; Baker, R. Jacob</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c445t-d40f1c4dbeda2439641759363347df8fe9d61c155498aa47adb140c2c7bee1563</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Automation, Laboratory - economics</topic><topic>Automation, Laboratory - methods</topic><topic>Costs and Cost Analysis</topic><topic>Electric Capacitance</topic><topic>Electrowetting - economics</topic><topic>Electrowetting - instrumentation</topic><topic>Electrowetting - methods</topic><topic>Microfluidics - economics</topic><topic>Microfluidics - instrumentation</topic><topic>Microfluidics - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Yiyan</creatorcontrib><creatorcontrib>Li, Hongzhong</creatorcontrib><creatorcontrib>Baker, R. Jacob</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of Laboratory Automation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Yiyan</au><au>Li, Hongzhong</au><au>Baker, R. Jacob</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Low-Cost and High-Resolution Droplet Position Detector for an Intelligent Electrowetting on Dielectric Device</atitle><jtitle>Journal of Laboratory Automation</jtitle><addtitle>J Lab Autom</addtitle><date>2015-12</date><risdate>2015</risdate><volume>20</volume><issue>6</issue><spage>663</spage><epage>669</epage><pages>663-669</pages><issn>2211-0682</issn><issn>2472-6303</issn><eissn>1540-2452</eissn><eissn>2211-0690</eissn><abstract>A low-cost and high-resolution capacitive-to-digital converter integrated circuit is used for droplet position detection in a digital microfluidic system. A field-programmable gate array FPGA is used as the integrated logic hub of the system for a highly reliable and efficient control of the circuit. A fast-fabricating PCB (printed circuit board) substrate microfluidic system is proposed. Smaller actuation threshold voltages than those previously reported are obtained. Droplets (3 µL) are actuated by using a 200 V, 500 Hz modulating pulsed voltage. Droplet positions can be detected and displayed on a PC-based 3D animation in real time. The actuators and the capacitance sensing circuits are implemented on one PCB to reduce the size of the system. With the capacitive droplet position detection system, the PCB-based electrowetting on dielectric device (EWOD) reported in this work has promise in automating immunohistochemistry experiments.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>25609255</pmid><doi>10.1177/2211068214566940</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2211-0682 |
| ispartof | Journal of Laboratory Automation, 2015-12, Vol.20 (6), p.663-669 |
| issn | 2211-0682 2472-6303 1540-2452 2211-0690 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1735331235 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Automation, Laboratory - economics Automation, Laboratory - methods Costs and Cost Analysis Electric Capacitance Electrowetting - economics Electrowetting - instrumentation Electrowetting - methods Microfluidics - economics Microfluidics - instrumentation Microfluidics - methods |
| title | A Low-Cost and High-Resolution Droplet Position Detector for an Intelligent Electrowetting on Dielectric Device |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T18%3A49%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Low-Cost%20and%20High-Resolution%20Droplet%20Position%20Detector%20for%20an%20Intelligent%20Electrowetting%20on%20Dielectric%20Device&rft.jtitle=Journal%20of%20Laboratory%20Automation&rft.au=Li,%20Yiyan&rft.date=2015-12&rft.volume=20&rft.issue=6&rft.spage=663&rft.epage=669&rft.pages=663-669&rft.issn=2211-0682&rft.eissn=1540-2452&rft_id=info:doi/10.1177/2211068214566940&rft_dat=%3Cproquest_cross%3E1735331235%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1735331235&rft_id=info:pmid/25609255&rft_sage_id=10.1177_2211068214566940&rfr_iscdi=true |