Targeted sequencing identifies patients with preclinical MDS at high risk of disease progression

The diagnosis of myelodysplastic syndromes (MDS) remains problematic due to the subjective nature of morphologic assessment. The reported high frequency of somatic mutations and increased structural variants by array-based cytogenetics have provided potential objective markers of disease; however, t...

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Veröffentlicht in:	Blood 2015-11, Vol.126 (21), p.2362-2365
Hauptverfasser:	Cargo, Catherine A., Rowbotham, Nicola, Evans, Paul A., Barrans, Sharon L., Bowen, David T., Crouch, Simon, Jack, Andrew S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Disease-Free Survival DNA Mutational Analysis Female Humans Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - mortality Male Mutation Myelodysplastic Syndromes - genetics Myelodysplastic Syndromes - mortality Retrospective Studies Risk Factors Survival Rate
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