Conformational control of cofactors in nature - the influence of protein-induced macrocycle distortion on the biological function of tetrapyrroles

Tetrapyrrole-containing proteins are one of the most fundamental classes of enzymes in nature and it remains an open question to give a chemical rationale for the multitude of biological reactions that can be catalyzed by these pigment-protein complexes. There are many fundamental processes where th...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2015-01, Vol.51 (96), p.17031-17063
Hauptverfasser: Senge, Mathias O, MacGowan, Stuart A, O'Brien, Jessica M
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Sprache:eng
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