Detection of aneuploidy by multicolor FISH in mouse sperm after in vivo treatment with acrylamide, colchicine, diazepam or thiabendazole

Multicolor fluorescence in situ hybridization (FISH) was used to investigate the induction of aneuploidy during meiosis in young adult male mice treated with chemicals chosen for the EU sponsored aneuploidy project (acrylamide, colchicine, diazepam and thiabendazole). The aim of the present study wa...

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Veröffentlicht in:	Mutagenesis 1999-03, Vol.14 (2), p.173-179
Hauptverfasser:	Schmid, T.E., Xu, Wang, Adler, I.-D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylamide - pharmacology Aneuploidy Animals Biological and medical sciences Bone Marrow Cells - metabolism Chemical mutagenesis Chromosome Aberrations - chemically induced Chromosome Disorders Colchicine - pharmacology Diazepam - pharmacology Dose-Response Relationship, Drug In Situ Hybridization, Fluorescence Male Medical sciences Mice Mice, Inbred C3H Spermatozoa - drug effects Spermatozoa - metabolism Thiabendazole - pharmacology Toxicology
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