Fracture healing redefined
Abstract It is well established that local mechanical conditions and interfragmentary movement are important factors for successful bone healing and may vary dramatically with patient fracture-load and activity. Up until now however it was technically impossible to use these key influence parameters...
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Veröffentlicht in: | Medical hypotheses 2015-12, Vol.85 (6), p.940-943 |
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description | Abstract It is well established that local mechanical conditions and interfragmentary movement are important factors for successful bone healing and may vary dramatically with patient fracture-load and activity. Up until now however it was technically impossible to use these key influence parameters in the aftercare treatment process of human lower extremity fractures. We propose a theory that with state of the art sensor technology these biomechanical influences can not only be monitored in vivo, but also used for individualized therapy protocols. Local measurement systems for fracture healing are available but remain research tools, due to various technical issues. To investigate the biomechanical influences on healing right away surrogate sensor tools are needed. Various gait characteristics have been proposed as surrogate measures. Currently available sensor tools could be modified with the appropriate support structure to allow such measurements continuously over the course of a fracture healing. Interdisciplinary work between clinicians, software engineers with computer and biomechanical simulations is needed. Through such a sensor system human boundary conditions for fracture healing could not only be defined for the first time, but also used for a unique, extendible aftercare system. With this tool critical healing situations would be detected much earlier and could be prevented with easy activity modifications, reducing patient and socioeconomic burden of disease. The hypothesis, necessary tools and support structures are presented. |
doi_str_mv | 10.1016/j.mehy.2015.09.006 |
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Up until now however it was technically impossible to use these key influence parameters in the aftercare treatment process of human lower extremity fractures. We propose a theory that with state of the art sensor technology these biomechanical influences can not only be monitored in vivo, but also used for individualized therapy protocols. Local measurement systems for fracture healing are available but remain research tools, due to various technical issues. To investigate the biomechanical influences on healing right away surrogate sensor tools are needed. Various gait characteristics have been proposed as surrogate measures. Currently available sensor tools could be modified with the appropriate support structure to allow such measurements continuously over the course of a fracture healing. Interdisciplinary work between clinicians, software engineers with computer and biomechanical simulations is needed. Through such a sensor system human boundary conditions for fracture healing could not only be defined for the first time, but also used for a unique, extendible aftercare system. With this tool critical healing situations would be detected much earlier and could be prevented with easy activity modifications, reducing patient and socioeconomic burden of disease. The hypothesis, necessary tools and support structures are presented.</description><identifier>ISSN: 0306-9877</identifier><identifier>EISSN: 1532-2777</identifier><identifier>DOI: 10.1016/j.mehy.2015.09.006</identifier><identifier>PMID: 26364044</identifier><language>eng</language><publisher>United States: Elsevier Ltd</publisher><subject>Biomechanical Phenomena ; Clinical Trials as Topic ; Computer Simulation ; Databases, Factual ; Female ; Fracture Healing - physiology ; Gait ; Humans ; Internal Medicine ; Male ; Software ; Tibial Fractures - therapy</subject><ispartof>Medical hypotheses, 2015-12, Vol.85 (6), p.940-943</ispartof><rights>Elsevier Ltd</rights><rights>2015 Elsevier Ltd</rights><rights>Copyright © 2015 Elsevier Ltd. 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Up until now however it was technically impossible to use these key influence parameters in the aftercare treatment process of human lower extremity fractures. We propose a theory that with state of the art sensor technology these biomechanical influences can not only be monitored in vivo, but also used for individualized therapy protocols. Local measurement systems for fracture healing are available but remain research tools, due to various technical issues. To investigate the biomechanical influences on healing right away surrogate sensor tools are needed. Various gait characteristics have been proposed as surrogate measures. Currently available sensor tools could be modified with the appropriate support structure to allow such measurements continuously over the course of a fracture healing. Interdisciplinary work between clinicians, software engineers with computer and biomechanical simulations is needed. Through such a sensor system human boundary conditions for fracture healing could not only be defined for the first time, but also used for a unique, extendible aftercare system. With this tool critical healing situations would be detected much earlier and could be prevented with easy activity modifications, reducing patient and socioeconomic burden of disease. The hypothesis, necessary tools and support structures are presented.</description><subject>Biomechanical Phenomena</subject><subject>Clinical Trials as Topic</subject><subject>Computer Simulation</subject><subject>Databases, Factual</subject><subject>Female</subject><subject>Fracture Healing - physiology</subject><subject>Gait</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Software</subject><subject>Tibial Fractures - therapy</subject><issn>0306-9877</issn><issn>1532-2777</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1Lw0AURQdRbK3-gS6kSzeJbz4ykwERpFgVBBfqekgmL3ZqmtSZROi_N7HVhQtXb3PuhXseIVMKMQUqL1fxGpfbmAFNYtAxgDwgY5pwFjGl1CEZAwcZ6VSpETkJYQUAWvD0mIyY5FKAEGMyXfjMtp3H2RKzytVvM48Flq7G4pQclVkV8Gx_J-R1cfsyv48en-4e5jePkRUpbSPkkhZpqXSCVDOppWWYcp6AtTorU0hoUXLLIVdCQJ5wKlgmc8VyUTCqZMon5GLXu_HNR4ehNWsXLFZVVmPTBUMV55pp-EbZDrW-CcFjaTberTO_NRTM4MSszODEDE4MaNM76UPn-_4uX2PxG_mR0ANXOwD7lZ8OvQnWYW2xcB5ta4rG_d9__Sdue5HOZtU7bjGsms7XvT9DTWAGzPPwleEpNAHolwn-BWaqhHA</recordid><startdate>20151201</startdate><enddate>20151201</enddate><creator>Braun, B.J</creator><creator>Rollmann, M</creator><creator>Veith, N</creator><creator>Pohlemann, T</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20151201</creationdate><title>Fracture healing redefined</title><author>Braun, B.J ; Rollmann, M ; Veith, N ; Pohlemann, T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-e361d8f795e192696c2e83350cc9af8051df3c30b7440b53142a6b72b4d217683</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Biomechanical Phenomena</topic><topic>Clinical Trials as Topic</topic><topic>Computer Simulation</topic><topic>Databases, Factual</topic><topic>Female</topic><topic>Fracture Healing - physiology</topic><topic>Gait</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Software</topic><topic>Tibial Fractures - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Braun, B.J</creatorcontrib><creatorcontrib>Rollmann, M</creatorcontrib><creatorcontrib>Veith, N</creatorcontrib><creatorcontrib>Pohlemann, T</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Medical hypotheses</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Braun, B.J</au><au>Rollmann, M</au><au>Veith, N</au><au>Pohlemann, T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fracture healing redefined</atitle><jtitle>Medical hypotheses</jtitle><addtitle>Med Hypotheses</addtitle><date>2015-12-01</date><risdate>2015</risdate><volume>85</volume><issue>6</issue><spage>940</spage><epage>943</epage><pages>940-943</pages><issn>0306-9877</issn><eissn>1532-2777</eissn><abstract>Abstract It is well established that local mechanical conditions and interfragmentary movement are important factors for successful bone healing and may vary dramatically with patient fracture-load and activity. Up until now however it was technically impossible to use these key influence parameters in the aftercare treatment process of human lower extremity fractures. We propose a theory that with state of the art sensor technology these biomechanical influences can not only be monitored in vivo, but also used for individualized therapy protocols. Local measurement systems for fracture healing are available but remain research tools, due to various technical issues. To investigate the biomechanical influences on healing right away surrogate sensor tools are needed. Various gait characteristics have been proposed as surrogate measures. Currently available sensor tools could be modified with the appropriate support structure to allow such measurements continuously over the course of a fracture healing. Interdisciplinary work between clinicians, software engineers with computer and biomechanical simulations is needed. Through such a sensor system human boundary conditions for fracture healing could not only be defined for the first time, but also used for a unique, extendible aftercare system. With this tool critical healing situations would be detected much earlier and could be prevented with easy activity modifications, reducing patient and socioeconomic burden of disease. The hypothesis, necessary tools and support structures are presented.</abstract><cop>United States</cop><pub>Elsevier Ltd</pub><pmid>26364044</pmid><doi>10.1016/j.mehy.2015.09.006</doi><tpages>4</tpages></addata></record> |
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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Biomechanical Phenomena Clinical Trials as Topic Computer Simulation Databases, Factual Female Fracture Healing - physiology Gait Humans Internal Medicine Male Software Tibial Fractures - therapy |
title | Fracture healing redefined |
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