Fracture healing redefined

Abstract It is well established that local mechanical conditions and interfragmentary movement are important factors for successful bone healing and may vary dramatically with patient fracture-load and activity. Up until now however it was technically impossible to use these key influence parameters...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Medical hypotheses 2015-12, Vol.85 (6), p.940-943
Hauptverfasser: Braun, B.J, Rollmann, M, Veith, N, Pohlemann, T
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 943
container_issue 6
container_start_page 940
container_title Medical hypotheses
container_volume 85
creator Braun, B.J
Rollmann, M
Veith, N
Pohlemann, T
description Abstract It is well established that local mechanical conditions and interfragmentary movement are important factors for successful bone healing and may vary dramatically with patient fracture-load and activity. Up until now however it was technically impossible to use these key influence parameters in the aftercare treatment process of human lower extremity fractures. We propose a theory that with state of the art sensor technology these biomechanical influences can not only be monitored in vivo, but also used for individualized therapy protocols. Local measurement systems for fracture healing are available but remain research tools, due to various technical issues. To investigate the biomechanical influences on healing right away surrogate sensor tools are needed. Various gait characteristics have been proposed as surrogate measures. Currently available sensor tools could be modified with the appropriate support structure to allow such measurements continuously over the course of a fracture healing. Interdisciplinary work between clinicians, software engineers with computer and biomechanical simulations is needed. Through such a sensor system human boundary conditions for fracture healing could not only be defined for the first time, but also used for a unique, extendible aftercare system. With this tool critical healing situations would be detected much earlier and could be prevented with easy activity modifications, reducing patient and socioeconomic burden of disease. The hypothesis, necessary tools and support structures are presented.
doi_str_mv 10.1016/j.mehy.2015.09.006
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1733929068</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0306987715003394</els_id><sourcerecordid>1733929068</sourcerecordid><originalsourceid>FETCH-LOGICAL-c481t-e361d8f795e192696c2e83350cc9af8051df3c30b7440b53142a6b72b4d217683</originalsourceid><addsrcrecordid>eNp9kU1Lw0AURQdRbK3-gS6kSzeJbz4ykwERpFgVBBfqekgmL3ZqmtSZROi_N7HVhQtXb3PuhXseIVMKMQUqL1fxGpfbmAFNYtAxgDwgY5pwFjGl1CEZAwcZ6VSpETkJYQUAWvD0mIyY5FKAEGMyXfjMtp3H2RKzytVvM48Flq7G4pQclVkV8Gx_J-R1cfsyv48en-4e5jePkRUpbSPkkhZpqXSCVDOppWWYcp6AtTorU0hoUXLLIVdCQJ5wKlgmc8VyUTCqZMon5GLXu_HNR4ehNWsXLFZVVmPTBUMV55pp-EbZDrW-CcFjaTberTO_NRTM4MSszODEDE4MaNM76UPn-_4uX2PxG_mR0ANXOwD7lZ8OvQnWYW2xcB5ta4rG_d9__Sdue5HOZtU7bjGsms7XvT9DTWAGzPPwleEpNAHolwn-BWaqhHA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1733929068</pqid></control><display><type>article</type><title>Fracture healing redefined</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Braun, B.J ; Rollmann, M ; Veith, N ; Pohlemann, T</creator><creatorcontrib>Braun, B.J ; Rollmann, M ; Veith, N ; Pohlemann, T</creatorcontrib><description>Abstract It is well established that local mechanical conditions and interfragmentary movement are important factors for successful bone healing and may vary dramatically with patient fracture-load and activity. Up until now however it was technically impossible to use these key influence parameters in the aftercare treatment process of human lower extremity fractures. We propose a theory that with state of the art sensor technology these biomechanical influences can not only be monitored in vivo, but also used for individualized therapy protocols. Local measurement systems for fracture healing are available but remain research tools, due to various technical issues. To investigate the biomechanical influences on healing right away surrogate sensor tools are needed. Various gait characteristics have been proposed as surrogate measures. Currently available sensor tools could be modified with the appropriate support structure to allow such measurements continuously over the course of a fracture healing. Interdisciplinary work between clinicians, software engineers with computer and biomechanical simulations is needed. Through such a sensor system human boundary conditions for fracture healing could not only be defined for the first time, but also used for a unique, extendible aftercare system. With this tool critical healing situations would be detected much earlier and could be prevented with easy activity modifications, reducing patient and socioeconomic burden of disease. The hypothesis, necessary tools and support structures are presented.</description><identifier>ISSN: 0306-9877</identifier><identifier>EISSN: 1532-2777</identifier><identifier>DOI: 10.1016/j.mehy.2015.09.006</identifier><identifier>PMID: 26364044</identifier><language>eng</language><publisher>United States: Elsevier Ltd</publisher><subject>Biomechanical Phenomena ; Clinical Trials as Topic ; Computer Simulation ; Databases, Factual ; Female ; Fracture Healing - physiology ; Gait ; Humans ; Internal Medicine ; Male ; Software ; Tibial Fractures - therapy</subject><ispartof>Medical hypotheses, 2015-12, Vol.85 (6), p.940-943</ispartof><rights>Elsevier Ltd</rights><rights>2015 Elsevier Ltd</rights><rights>Copyright © 2015 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-e361d8f795e192696c2e83350cc9af8051df3c30b7440b53142a6b72b4d217683</citedby><cites>FETCH-LOGICAL-c481t-e361d8f795e192696c2e83350cc9af8051df3c30b7440b53142a6b72b4d217683</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.mehy.2015.09.006$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26364044$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Braun, B.J</creatorcontrib><creatorcontrib>Rollmann, M</creatorcontrib><creatorcontrib>Veith, N</creatorcontrib><creatorcontrib>Pohlemann, T</creatorcontrib><title>Fracture healing redefined</title><title>Medical hypotheses</title><addtitle>Med Hypotheses</addtitle><description>Abstract It is well established that local mechanical conditions and interfragmentary movement are important factors for successful bone healing and may vary dramatically with patient fracture-load and activity. Up until now however it was technically impossible to use these key influence parameters in the aftercare treatment process of human lower extremity fractures. We propose a theory that with state of the art sensor technology these biomechanical influences can not only be monitored in vivo, but also used for individualized therapy protocols. Local measurement systems for fracture healing are available but remain research tools, due to various technical issues. To investigate the biomechanical influences on healing right away surrogate sensor tools are needed. Various gait characteristics have been proposed as surrogate measures. Currently available sensor tools could be modified with the appropriate support structure to allow such measurements continuously over the course of a fracture healing. Interdisciplinary work between clinicians, software engineers with computer and biomechanical simulations is needed. Through such a sensor system human boundary conditions for fracture healing could not only be defined for the first time, but also used for a unique, extendible aftercare system. With this tool critical healing situations would be detected much earlier and could be prevented with easy activity modifications, reducing patient and socioeconomic burden of disease. The hypothesis, necessary tools and support structures are presented.</description><subject>Biomechanical Phenomena</subject><subject>Clinical Trials as Topic</subject><subject>Computer Simulation</subject><subject>Databases, Factual</subject><subject>Female</subject><subject>Fracture Healing - physiology</subject><subject>Gait</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Software</subject><subject>Tibial Fractures - therapy</subject><issn>0306-9877</issn><issn>1532-2777</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1Lw0AURQdRbK3-gS6kSzeJbz4ykwERpFgVBBfqekgmL3ZqmtSZROi_N7HVhQtXb3PuhXseIVMKMQUqL1fxGpfbmAFNYtAxgDwgY5pwFjGl1CEZAwcZ6VSpETkJYQUAWvD0mIyY5FKAEGMyXfjMtp3H2RKzytVvM48Flq7G4pQclVkV8Gx_J-R1cfsyv48en-4e5jePkRUpbSPkkhZpqXSCVDOppWWYcp6AtTorU0hoUXLLIVdCQJ5wKlgmc8VyUTCqZMon5GLXu_HNR4ehNWsXLFZVVmPTBUMV55pp-EbZDrW-CcFjaTberTO_NRTM4MSszODEDE4MaNM76UPn-_4uX2PxG_mR0ANXOwD7lZ8OvQnWYW2xcB5ta4rG_d9__Sdue5HOZtU7bjGsms7XvT9DTWAGzPPwleEpNAHolwn-BWaqhHA</recordid><startdate>20151201</startdate><enddate>20151201</enddate><creator>Braun, B.J</creator><creator>Rollmann, M</creator><creator>Veith, N</creator><creator>Pohlemann, T</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20151201</creationdate><title>Fracture healing redefined</title><author>Braun, B.J ; Rollmann, M ; Veith, N ; Pohlemann, T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-e361d8f795e192696c2e83350cc9af8051df3c30b7440b53142a6b72b4d217683</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Biomechanical Phenomena</topic><topic>Clinical Trials as Topic</topic><topic>Computer Simulation</topic><topic>Databases, Factual</topic><topic>Female</topic><topic>Fracture Healing - physiology</topic><topic>Gait</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Software</topic><topic>Tibial Fractures - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Braun, B.J</creatorcontrib><creatorcontrib>Rollmann, M</creatorcontrib><creatorcontrib>Veith, N</creatorcontrib><creatorcontrib>Pohlemann, T</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Medical hypotheses</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Braun, B.J</au><au>Rollmann, M</au><au>Veith, N</au><au>Pohlemann, T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fracture healing redefined</atitle><jtitle>Medical hypotheses</jtitle><addtitle>Med Hypotheses</addtitle><date>2015-12-01</date><risdate>2015</risdate><volume>85</volume><issue>6</issue><spage>940</spage><epage>943</epage><pages>940-943</pages><issn>0306-9877</issn><eissn>1532-2777</eissn><abstract>Abstract It is well established that local mechanical conditions and interfragmentary movement are important factors for successful bone healing and may vary dramatically with patient fracture-load and activity. Up until now however it was technically impossible to use these key influence parameters in the aftercare treatment process of human lower extremity fractures. We propose a theory that with state of the art sensor technology these biomechanical influences can not only be monitored in vivo, but also used for individualized therapy protocols. Local measurement systems for fracture healing are available but remain research tools, due to various technical issues. To investigate the biomechanical influences on healing right away surrogate sensor tools are needed. Various gait characteristics have been proposed as surrogate measures. Currently available sensor tools could be modified with the appropriate support structure to allow such measurements continuously over the course of a fracture healing. Interdisciplinary work between clinicians, software engineers with computer and biomechanical simulations is needed. Through such a sensor system human boundary conditions for fracture healing could not only be defined for the first time, but also used for a unique, extendible aftercare system. With this tool critical healing situations would be detected much earlier and could be prevented with easy activity modifications, reducing patient and socioeconomic burden of disease. The hypothesis, necessary tools and support structures are presented.</abstract><cop>United States</cop><pub>Elsevier Ltd</pub><pmid>26364044</pmid><doi>10.1016/j.mehy.2015.09.006</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0306-9877
ispartof Medical hypotheses, 2015-12, Vol.85 (6), p.940-943
issn 0306-9877
1532-2777
language eng
recordid cdi_proquest_miscellaneous_1733929068
source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Biomechanical Phenomena
Clinical Trials as Topic
Computer Simulation
Databases, Factual
Female
Fracture Healing - physiology
Gait
Humans
Internal Medicine
Male
Software
Tibial Fractures - therapy
title Fracture healing redefined
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T20%3A33%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Fracture%20healing%20redefined&rft.jtitle=Medical%20hypotheses&rft.au=Braun,%20B.J&rft.date=2015-12-01&rft.volume=85&rft.issue=6&rft.spage=940&rft.epage=943&rft.pages=940-943&rft.issn=0306-9877&rft.eissn=1532-2777&rft_id=info:doi/10.1016/j.mehy.2015.09.006&rft_dat=%3Cproquest_cross%3E1733929068%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1733929068&rft_id=info:pmid/26364044&rft_els_id=S0306987715003394&rfr_iscdi=true