Influence of environmental cadmium on testicular proliferation in roe deer
The influence of cadmium on spermatogenesis in roe deer was studied, comparing animals from areas with high ( n = 37) and low ( n = 23) cadmium exposure. Testes were evaluated during pre-rut (May) and rut (July/August). During these periods the cadmium accumulation (mg/kg kidney) in polluted regions...
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| Veröffentlicht in: | Reproductive toxicology (Elmsford, N.Y.) N.Y.), 1999-07, Vol.13 (4), p.261-267 |
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| container_title | Reproductive toxicology (Elmsford, N.Y.) |
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| creator | Blottner, Steffen Frölich, Kai Roelants, Hannelore Streich, Jürgen Tataruch, Frieda |
| description | The influence of cadmium on spermatogenesis in roe deer was studied, comparing animals from areas with high (
n = 37) and low (
n = 23) cadmium exposure. Testes were evaluated during pre-rut (May) and rut (July/August). During these periods the cadmium accumulation (mg/kg kidney) in polluted regions averaged 3.41 and 3.52 in comparison with 1.61 and 1.81 in controls. Cadmium accumulation was positively correlated with testis weight during both seasons. In May the proliferation (units of tissue polypeptid specific antigen/g parenchyma) was lower in animals with higher cadmium (24.02 compared with 78.20;
P < 0.01). During the rut, testicular proliferation and spermatozoa/g testis as well as apoptosis showed no significant changes with increased cadmium contamination. The results suggest delayed proliferation during the pre-rutting period in animals with high cadmium exposure, but other indications of effects on the testis were not significant. |
| doi_str_mv | 10.1016/S0890-6238(99)00014-3 |
| format | Article |
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n = 37) and low (
n = 23) cadmium exposure. Testes were evaluated during pre-rut (May) and rut (July/August). During these periods the cadmium accumulation (mg/kg kidney) in polluted regions averaged 3.41 and 3.52 in comparison with 1.61 and 1.81 in controls. Cadmium accumulation was positively correlated with testis weight during both seasons. In May the proliferation (units of tissue polypeptid specific antigen/g parenchyma) was lower in animals with higher cadmium (24.02 compared with 78.20;
P < 0.01). During the rut, testicular proliferation and spermatozoa/g testis as well as apoptosis showed no significant changes with increased cadmium contamination. The results suggest delayed proliferation during the pre-rutting period in animals with high cadmium exposure, but other indications of effects on the testis were not significant.</description><identifier>ISSN: 0890-6238</identifier><identifier>EISSN: 1873-1708</identifier><identifier>DOI: 10.1016/S0890-6238(99)00014-3</identifier><identifier>PMID: 10453910</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Animal, plant and microbial ecology ; Animals ; Apoptosis ; Applied ecology ; Biological and medical sciences ; Cadmium ; Cadmium - pharmacokinetics ; Cadmium - toxicity ; Cell Division - drug effects ; Deer - physiology ; Dose-Response Relationship, Drug ; Ecotoxicology, biological effects of pollution ; Effects of pollution and side effects of pesticides on vertebrates ; Environmental Pollutants - pharmacokinetics ; Environmental Pollutants - toxicity ; Fundamental and applied biological sciences. Psychology ; Lead ; Male ; Mammalia ; Proliferation ; Roe deer ; Season ; Seasons ; Spermatogenesis ; Spermatogenesis - drug effects ; Spermatozoa - drug effects ; Spermatozoa - physiology ; Testis ; Testis - cytology ; Testis - drug effects ; Testis - physiology</subject><ispartof>Reproductive toxicology (Elmsford, N.Y.), 1999-07, Vol.13 (4), p.261-267</ispartof><rights>1999 Elsevier Inc.</rights><rights>2000 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-2e92d5a7a10092662233ed9a2bc657cfb2644baab5dc0a43080eaba28a20e1f33</citedby><cites>FETCH-LOGICAL-c421t-2e92d5a7a10092662233ed9a2bc657cfb2644baab5dc0a43080eaba28a20e1f33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0890-6238(99)00014-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>310,311,315,781,785,790,791,3551,23934,23935,25144,27928,27929,45999</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1529344$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10453910$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Blottner, Steffen</creatorcontrib><creatorcontrib>Frölich, Kai</creatorcontrib><creatorcontrib>Roelants, Hannelore</creatorcontrib><creatorcontrib>Streich, Jürgen</creatorcontrib><creatorcontrib>Tataruch, Frieda</creatorcontrib><title>Influence of environmental cadmium on testicular proliferation in roe deer</title><title>Reproductive toxicology (Elmsford, N.Y.)</title><addtitle>Reprod Toxicol</addtitle><description>The influence of cadmium on spermatogenesis in roe deer was studied, comparing animals from areas with high (
n = 37) and low (
n = 23) cadmium exposure. Testes were evaluated during pre-rut (May) and rut (July/August). During these periods the cadmium accumulation (mg/kg kidney) in polluted regions averaged 3.41 and 3.52 in comparison with 1.61 and 1.81 in controls. Cadmium accumulation was positively correlated with testis weight during both seasons. In May the proliferation (units of tissue polypeptid specific antigen/g parenchyma) was lower in animals with higher cadmium (24.02 compared with 78.20;
P < 0.01). During the rut, testicular proliferation and spermatozoa/g testis as well as apoptosis showed no significant changes with increased cadmium contamination. The results suggest delayed proliferation during the pre-rutting period in animals with high cadmium exposure, but other indications of effects on the testis were not significant.</description><subject>Animal, plant and microbial ecology</subject><subject>Animals</subject><subject>Apoptosis</subject><subject>Applied ecology</subject><subject>Biological and medical sciences</subject><subject>Cadmium</subject><subject>Cadmium - pharmacokinetics</subject><subject>Cadmium - toxicity</subject><subject>Cell Division - drug effects</subject><subject>Deer - physiology</subject><subject>Dose-Response Relationship, Drug</subject><subject>Ecotoxicology, biological effects of pollution</subject><subject>Effects of pollution and side effects of pesticides on vertebrates</subject><subject>Environmental Pollutants - pharmacokinetics</subject><subject>Environmental Pollutants - toxicity</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Lead</subject><subject>Male</subject><subject>Mammalia</subject><subject>Proliferation</subject><subject>Roe deer</subject><subject>Season</subject><subject>Seasons</subject><subject>Spermatogenesis</subject><subject>Spermatogenesis - drug effects</subject><subject>Spermatozoa - drug effects</subject><subject>Spermatozoa - physiology</subject><subject>Testis</subject><subject>Testis - cytology</subject><subject>Testis - drug effects</subject><subject>Testis - physiology</subject><issn>0890-6238</issn><issn>1873-1708</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMlKxUAQRRtR9Dl8gpKFiC6i1UOGXomIIw9cqOum0qlAS9LR7kTw780bUHeualGn6l4OY4cczjnw_OIZSg1pLmR5qvUZAHCVyg0242UhU15AuclmP8gO243xbYJUoYtttsNBZVJzmLHHB9-0I3lLSd8k5D9d6H1HfsA2sVh3buyS3icDxcHZscWQvIe-dQ0FHNy0cD4JPSU1UdhnWw22kQ7Wc4-93t68XN-n86e7h-ureWqV4EMqSIs6wwI5gBZ5LoSUVGsUlc2zwjaVyJWqEKustoBKQgmEFYoSBRBvpNxjJ6u_U5OPcSpmOhcttS166sdoeCFloWU2gdkKtKGPMVBj3oPrMHwZDmYh0SwlmoUho7VZSjSLgKN1wFh1VP-5WlmbgOM1gNFi2wT01sVfLhNaKjVhlyuMJhufjoKJ1i1U1y6QHUzdu3-afAO0to5d</recordid><startdate>19990701</startdate><enddate>19990701</enddate><creator>Blottner, Steffen</creator><creator>Frölich, Kai</creator><creator>Roelants, Hannelore</creator><creator>Streich, Jürgen</creator><creator>Tataruch, Frieda</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>19990701</creationdate><title>Influence of environmental cadmium on testicular proliferation in roe deer</title><author>Blottner, Steffen ; Frölich, Kai ; Roelants, Hannelore ; Streich, Jürgen ; Tataruch, Frieda</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-2e92d5a7a10092662233ed9a2bc657cfb2644baab5dc0a43080eaba28a20e1f33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Animal, plant and microbial ecology</topic><topic>Animals</topic><topic>Apoptosis</topic><topic>Applied ecology</topic><topic>Biological and medical sciences</topic><topic>Cadmium</topic><topic>Cadmium - pharmacokinetics</topic><topic>Cadmium - toxicity</topic><topic>Cell Division - drug effects</topic><topic>Deer - physiology</topic><topic>Dose-Response Relationship, Drug</topic><topic>Ecotoxicology, biological effects of pollution</topic><topic>Effects of pollution and side effects of pesticides on vertebrates</topic><topic>Environmental Pollutants - pharmacokinetics</topic><topic>Environmental Pollutants - toxicity</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Lead</topic><topic>Male</topic><topic>Mammalia</topic><topic>Proliferation</topic><topic>Roe deer</topic><topic>Season</topic><topic>Seasons</topic><topic>Spermatogenesis</topic><topic>Spermatogenesis - drug effects</topic><topic>Spermatozoa - drug effects</topic><topic>Spermatozoa - physiology</topic><topic>Testis</topic><topic>Testis - cytology</topic><topic>Testis - drug effects</topic><topic>Testis - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Blottner, Steffen</creatorcontrib><creatorcontrib>Frölich, Kai</creatorcontrib><creatorcontrib>Roelants, Hannelore</creatorcontrib><creatorcontrib>Streich, Jürgen</creatorcontrib><creatorcontrib>Tataruch, Frieda</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Reproductive toxicology (Elmsford, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Blottner, Steffen</au><au>Frölich, Kai</au><au>Roelants, Hannelore</au><au>Streich, Jürgen</au><au>Tataruch, Frieda</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of environmental cadmium on testicular proliferation in roe deer</atitle><jtitle>Reproductive toxicology (Elmsford, N.Y.)</jtitle><addtitle>Reprod Toxicol</addtitle><date>1999-07-01</date><risdate>1999</risdate><volume>13</volume><issue>4</issue><spage>261</spage><epage>267</epage><pages>261-267</pages><issn>0890-6238</issn><eissn>1873-1708</eissn><abstract>The influence of cadmium on spermatogenesis in roe deer was studied, comparing animals from areas with high (
n = 37) and low (
n = 23) cadmium exposure. Testes were evaluated during pre-rut (May) and rut (July/August). During these periods the cadmium accumulation (mg/kg kidney) in polluted regions averaged 3.41 and 3.52 in comparison with 1.61 and 1.81 in controls. Cadmium accumulation was positively correlated with testis weight during both seasons. In May the proliferation (units of tissue polypeptid specific antigen/g parenchyma) was lower in animals with higher cadmium (24.02 compared with 78.20;
P < 0.01). During the rut, testicular proliferation and spermatozoa/g testis as well as apoptosis showed no significant changes with increased cadmium contamination. The results suggest delayed proliferation during the pre-rutting period in animals with high cadmium exposure, but other indications of effects on the testis were not significant.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>10453910</pmid><doi>10.1016/S0890-6238(99)00014-3</doi><tpages>7</tpages></addata></record> |
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| subjects | Animal, plant and microbial ecology Animals Apoptosis Applied ecology Biological and medical sciences Cadmium Cadmium - pharmacokinetics Cadmium - toxicity Cell Division - drug effects Deer - physiology Dose-Response Relationship, Drug Ecotoxicology, biological effects of pollution Effects of pollution and side effects of pesticides on vertebrates Environmental Pollutants - pharmacokinetics Environmental Pollutants - toxicity Fundamental and applied biological sciences. Psychology Lead Male Mammalia Proliferation Roe deer Season Seasons Spermatogenesis Spermatogenesis - drug effects Spermatozoa - drug effects Spermatozoa - physiology Testis Testis - cytology Testis - drug effects Testis - physiology |
| title | Influence of environmental cadmium on testicular proliferation in roe deer |
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