A murine model of IgE-mediated cow’s milk hypersensitivity

Background: Cow’s milk allergy (CMA) is one of the leading causes of food allergy in children. Understanding the mechanisms involved in the development of CMA has been hampered by the lack of suitable animal models. Objective: We sought to develop a mouse model of IgE-mediated cow’s milk hypersensit...

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Veröffentlicht in:	Journal of allergy and clinical immunology 1999-02, Vol.103 (2), p.206-214
Hauptverfasser:	Li, Xiu-min, Schofield, Brian H., Huang, Chih-Kang, Kleiner, Gary I., Sampson, Hugh A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - toxicity Anaphylaxis - etiology Anaphylaxis - immunology Anaphylaxis - pathology Animals Biological and medical sciences Capillary Permeability Caseins - blood Cell Degranulation Cholera Toxin - immunology Cholera Toxin - toxicity cow Cytokines - biosynthesis Disease Models, Animal Enzyme-Linked Immunosorbent Assay Experimental and animal immunopathology. Animal models Female Food allergy Histamine - blood IgE Immunoglobulin E - blood Immunoglobulin E - immunology Immunopathology Intestines - pathology mast cell Mast Cells - immunology Mast Cells - pathology Medical sciences Mice Mice, Inbred C3H Milk Hypersensitivity - blood Milk Hypersensitivity - immunology Milk Hypersensitivity - pathology murine model s milk hypersensitivity Skin - pathology Spleen - cytology T-Lymphocytes - immunology T-Lymphocytes - metabolism Th2 Cells - metabolism
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