Refined Solution Structure of the C-Terminal DNA-Binding Domain of Human Immunovirus-1 Integrase

The structure of the C-terminal DNA-binding domain of human immunovirus-1 integrase has been refined using nuclear magnetic resonance spectroscopy. The protein is a dimer in solution and shows a well-defined dimer interface. The folding topology of the monomer consists of a five-stranded beta -barre...

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Veröffentlicht in:Proteins, structure, function, and bioinformatics structure, function, and bioinformatics, 1999-09, Vol.36 (4), p.556-564
Hauptverfasser: Eijkelenboom, APAM, Sprangers, R, Haerd, K, Lutzke, RAP, Plasterk, RHA, Boelens, R, Kaptein, R
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Sprache:eng
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