Blood DNA methylation biomarkers predict clinical reactivity in food-sensitized infants

Background The diagnosis of food allergy (FA) can be challenging because approximately half of food-sensitized patients are asymptomatic. Current diagnostic tests are excellent makers of sensitization but poor predictors of clinical reactivity. Thus oral food challenges (OFCs) are required to determ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of allergy and clinical immunology 2015-05, Vol.135 (5), p.1319-1328.e12
Hauptverfasser:	Martino, David, PhD, Dang, Thanh, PhD, Sexton-Oates, Alexandra, BSc, Prescott, Susan, MBBS, FRACP, PhD, Tang, Mimi L.K., MBBS, PhD, FRACP, FRCPA, FAAAAI, Dharmage, Shyamali, MBBS, MSc, MD, PhD, Gurrin, Lyle, PhD, Koplin, Jennifer, PhD, Ponsonby, Anne-Louise, MD, PhD, Allen, Katrina J., MBBS, FRACP, FAAAAI, PhD, Saffery, Richard, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Allergy and Immunology allergy epigenetics Biomarkers Blood Computational Biology CpG Islands DNA Methylation DNA methylation profiling Epigenesis, Genetic epigenetic epidemiology epigenetics Food allergies Food allergy Food Hypersensitivity - diagnosis Food Hypersensitivity - genetics Food Hypersensitivity - immunology Gene Expression Profiling Humans Immunoglobulin E - blood Immunoglobulin E - immunology Infant Infinium Leukocytes, Mononuclear - immunology Leukocytes, Mononuclear - metabolism methylation profiling Models, Biological Molecular Sequence Annotation Prognosis Reproducibility of Results Sensitivity and Specificity shrunken centroids
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!