Effects of charge and surface ligand properties of nanoparticles on oxidative stress and gene expression within the gut of Daphnia magna

•ROS generation by cells is highest in charged ligand nanoparticle combinations.•The same level of ROS response is not observed in ligands alone.•Positively charged PAH-AuNPs at high dose upregulate gst and hsp70 genes.•Negatively charged citrate-AuNPs elicit a dose response expression of mt1 gene.•...

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Veröffentlicht in:	Aquatic Toxicology, 162:1-9 162:1-9, 2015-05, Vol.162, p.1-9
Hauptverfasser:	Dominguez, Gustavo A., Lohse, Samuel E., Torelli, Marco D., Murphy, Catherine J., Hamers, Robert J., Orr, Galya, Klaper, Rebecca D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Daphnia - drug effects Daphnia - genetics Daphnia - metabolism Daphnia magna Digestive System - drug effects Digestive System - metabolism Environmental Molecular Sciences Laboratory Female gene Gene expression Gene Expression - drug effects Gold - chemistry Gold - toxicity gst Ligand Ligands nanoparticles Nanoparticles - adverse effects Nanoparticles - chemistry Nanotoxicity oxidative Oxidative stress Oxidative Stress - drug effects Oxidative Stress - genetics ROS Static Electricity Water - metabolism Water Pollutants, Chemical - chemistry Water Pollutants, Chemical - toxicity
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