Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators: e0136423

Estrogen receptor alpha (ER alpha ), as a ligand-dependent transcription factor, mediates 17[Beta]-estradiol (E2) effects. ER alpha is a modular protein containing a DNA binding domain (DBD) and transcription activation domains (AD) located at the amino- and carboxyl-termini. The interaction of the...

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Veröffentlicht in:PloS one 2015-08, Vol.10 (8)
Hauptverfasser: Muyan, Mesut, Guepuer, Gizem, Yasar, Pelin, Ayaz, Gamze, User, Sirma Damla, Kazan, Hasan Hueseyin, Huang, Yanfang
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Sprache:eng
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