Individual genome sequencing identified a novel enhancer element in exon 7 of the CSFR1 gene by shift of expressed allele ratios

The sequencing of individual genetic information may provide a powerful tool for elucidating the mechanism by which individual SNPs affect promoter function. Here, we assessed the genome of a Russian male that was previously sequenced. The RNA-Seq data from blood cells revealed 234 candidate transcr...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Gene 2015-07, Vol.566 (2), p.223-228
Hauptverfasser:	Zhenilo, S., Khrameeva, E., Tsygankova, S., Zhigalova, N., Mazur, A., Prokhortchouk, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Biallelic transcription Chromatin Immunoprecipitation CSF1R Enhancer Elements, Genetic Exons HEK293 Cells Humans Polymorphism, Single Nucleotide Receptors, Colony-Stimulating Factor - genetics RNA-seq SNP
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!