The CASC15 Long Intergenic Noncoding RNA Locus Is Involved in Melanoma Progression and Phenotype Switching

In recent years, considerable advances have been made in the characterization of protein-coding alterations involved in the pathogenesis of melanoma. However, despite their growing implication in cancer, little is known about the role of long noncoding RNAs in melanoma progression. We hypothesized t...

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Veröffentlicht in:	Journal of investigative dermatology 2015-10, Vol.135 (10), p.2464-2474
Hauptverfasser:	Lessard, Laurent, Liu, Michelle, Marzese, Diego M., Wang, Hongwei, Chong, Kelly, Kawas, Neal, Donovan, Nicholas C., Kiyohara, Eiji, Hsu, Sandy, Nelson, Nellie, Izraely, Sivan, Sagi-Assif, Orit, Witz, Isaac P., Ma, Xiao-Jun, Luo, Yuling, Hoon, Dave S.B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biopsy, Needle Chromosomes, Human, Pair 6 - genetics Disease Progression Gene Expression Profiling Gene Expression Regulation, Neoplastic - genetics Genetic Loci - genetics Humans Immunohistochemistry Melanocytes - pathology Melanoma - genetics Melanoma - pathology Mice Phenotype Real-Time Polymerase Chain Reaction - methods RNA, Long Noncoding - genetics Skin Neoplasms - genetics Skin Neoplasms - pathology Tumor Cells, Cultured
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