Association of OPG gene polymorphism with susceptibility to rheumatoid arthrits in Chinese Han

Highlights • The pathogenesis of rheumatoid arthritis is unclear. • To investigate the association of osteoproterin gene polymorphisms. • The OPG gene 163A/G SNP may be associated with RA susceptibility. • G allele of 163A/G SNP may be the risk factor for developing RA.

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Bibliographische Detailangaben
Veröffentlicht in:	Immunology letters 2015-06, Vol.165 (2), p.102-106
Hauptverfasser:	Cai, Yue-ming, Wang, Jing, Wang, Qing-wen, Long, Xia, Wang, Wei-guang, Zhang, Lu, Zeng, Hui-ping, Wu, Zhi-cheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Allergy and Immunology Arthritis, Rheumatoid - genetics Case-Control Studies China Female Gene Frequency Genetic Association Studies Genetic Predisposition to Disease Genotype Humans Male Middle Aged OPG Osteoprotegerin - genetics Polymorphism Polymorphism, Single Nucleotide Rheumatoid arthritis Risk Single nucleotide Young Adult
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Beschreibung
Zusammenfassung:	Highlights • The pathogenesis of rheumatoid arthritis is unclear. • To investigate the association of osteoproterin gene polymorphisms. • The OPG gene 163A/G SNP may be associated with RA susceptibility. • G allele of 163A/G SNP may be the risk factor for developing RA.
ISSN:	0165-2478 1879-0542
DOI:	10.1016/j.imlet.2014.07.011