Peptide display on a surface loop of human parvovirus B19 VP2: Assembly and characterization of virus-like particles

•Surface loop 62–75 of the structural protein VP2 of or parvovirus B19 was selected to insert a heterologous peptide F215–278.•Chimeric protein VP2-F215–278 retains its ability to fold and self-assemble into VLPs.•VP2 and VP2-F215–278 can also co-self-assemble into hybrid VLPs.•Changes in colloidal...

Ausführliche Beschreibung