Anti-type II collagen antibodies detection and avidity in patients with oligoarticular and polyarticular forms of juvenile idiopathic arthritis

Highlights • Anti-type II collagen antibodies are present in patients with oligoarticular and polyarticular forms of JIA. • Anti-type II collagen antibody detection is significantly higher in patients with JIA of ≤6 months duration. • Antibodies displaying high avidity to type II collagen is associa...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Immunology letters 2015-05, Vol.165 (1), p.20-25
Hauptverfasser:	Araujo, Galber R, Fonseca, João E, Fujimura, Patricia T, Cunha-Junior, Jair P, Silva, Carlos H.M, Mourão, Ana F, Canhão, Helena, Goulart, Luiz R, Gonçalves, João, Ueira-Vieira, Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Allergy and Immunology Antibody Affinity - immunology Arthritis, Juvenile - diagnosis Arthritis, Juvenile - immunology Autoantibodies - blood Autoantibodies - immunology Case-Control Studies Child Collagen Type II - immunology Enzyme-Linked Immunosorbent Assay Female Humans Immunoglobulin G - blood Immunoglobulin G - immunology Juvenile idiopathic arthritis Male Serodiagnosis Type II collagen Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Anti-type II collagen antibodies are present in patients with oligoarticular and polyarticular forms of JIA. • Anti-type II collagen antibody detection is significantly higher in patients with JIA of ≤6 months duration. • Antibodies displaying high avidity to type II collagen is associated with disease activity.
ISSN:	0165-2478 1879-0542
DOI:	10.1016/j.imlet.2015.03.006