MiR-103 inhibits osteoblast proliferation mainly through suppressing Cav1.2 expression in simulated microgravity

Abstract Emerging evidence indicates that microRNAs (miRNAs) play important roles in modulating osteoblast function and bone formation. However, the influence of miRNA on osteoblast proliferation and the possible mechanisms underlying remain to be defined. In this study, we aimed to investigate whet...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2015-07, Vol.76, p.121-128
Hauptverfasser:	Sun, Zhongyang, Cao, Xinsheng, Hu, Zebing, Zhang, Lianchang, Wang, Han, Zhou, Hua, Li, Dongtao, Zhang, Shu, Xie, Manjiang
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Calcium Channels, L-Type - metabolism Cav1.2 Cell proliferation Cell Proliferation - physiology Mice MicroRNAs - genetics MicroRNAs - physiology MiR-103 Orthopedics Osteoblasts Osteoblasts - cytology Simulated microgravity Up-Regulation Weightlessness
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