Novel ageing-biomarker discovery using data-intensive technologies

•Hypothesis-free transcript- and prote-omic approaches were used to study ageing.•We identify novel putative biomarkers of human healthy ageing.•We describe high throughput analyses for evaluating novel biomarkers.•Next generation sequencing and shotgun proteomics are now choice biomarker methods. A...

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Veröffentlicht in:	Mechanisms of ageing and development 2015-11, Vol.151, p.114-121
Hauptverfasser:	Griffiths, H.R., Augustyniak, E.M., Bennett, S.J., Debacq-Chainiaux, F., Dunston, C.R., Kristensen, P., Melchjorsen, C.J., Navarrete, Santos A., Simm, A., Toussaint, O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aging - metabolism Biomarker discovery Biomarkers - metabolism Data Mining - methods Endothelial progenitor cells Humans Hyperoxia miR array Proteomics Software
Online-Zugang:	Volltext
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