Sensorimotor returning in complex regional pain syndrome parallels pain reduction
Patients with complex regional pain syndrome (CRPS) and intractable pain showed a shrinkage of cortical maps on primary (SI) and secondary somatosensory cortex (SII) contralateral to the affected limb. This was paralleled by an impairment of the two‐point discrimination thresholds. Behavioral treatm...
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| Veröffentlicht in: | Annals of neurology 2005-03, Vol.57 (3), p.425-429 |
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| container_end_page | 429 |
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| container_issue | 3 |
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| container_title | Annals of neurology |
| container_volume | 57 |
| creator | Pleger, Burkhard Tegenthoff, Martin Ragert, Patrick Förster, Ann-Freya Dinse, Hubert R. Schwenkreis, Peter Nicolas, Volkmar Maier, Christoph |
| description | Patients with complex regional pain syndrome (CRPS) and intractable pain showed a shrinkage of cortical maps on primary (SI) and secondary somatosensory cortex (SII) contralateral to the affected limb. This was paralleled by an impairment of the two‐point discrimination thresholds. Behavioral treatment over 1 to 6 months consisting of graded sensorimotor retuning led to a persistent decrease in pain intensity, which was accompanied by a restoration of the impaired tactile discrimination and regaining of cortical map size in contralateral SI and SII. This suggests that the reversal of tactile impairment and cortical reorganization in CRPS is associated with a decrease in pain. Ann Neurol 2005;57:425–429 |
| doi_str_mv | 10.1002/ana.20394 |
| format | Article |
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Psychology</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. 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| ispartof | Annals of neurology, 2005-03, Vol.57 (3), p.425-429 |
| issn | 0364-5134 1531-8249 |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Biological and medical sciences Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction Fundamental and applied biological sciences. Psychology Medical sciences Nervous system (semeiology, syndromes) Neurology Somesthesis and somesthetic pathways (proprioception, exteroception, nociception) interoception electrolocation. Sensory receptors Vertebrates: nervous system and sense organs |
| title | Sensorimotor returning in complex regional pain syndrome parallels pain reduction |
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