Is genistein neuroprotective in traumatic brain injury?

Abstract The concerns about negative consequences of estrogen therapy have led to introduce other strategies to obtain estrogen's benefits in the brain. The present study tests the hypothesis that a major isoflavone of soy; genistein with estrogen-like activity can be neuroprotective in traumat...

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Veröffentlicht in:	Physiology & behavior 2015-12, Vol.152 (Pt A), p.26-31
Hauptverfasser:	Soltani, Zahra, Khaksari, Mohammad, Jafari, Elham, Iranpour, Maryam, Shahrokhi, Nader
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood-Brain Barrier - drug effects Blood-Brain Barrier - pathology Blood-Brain Barrier - physiopathology Blood–brain barrier Brain - drug effects Brain - pathology Brain - physiopathology Brain edema Brain Edema - drug therapy Brain Edema - pathology Brain Edema - physiopathology Brain Injuries - drug therapy Brain Injuries - pathology Brain Injuries - physiopathology Brain injury Capillary Permeability - drug effects Capillary Permeability - physiology Dimethyl Sulfoxide - pharmacology Disease Models, Animal Genistein - pharmacology Intracranial pressure Intracranial Pressure - drug effects Intracranial Pressure - physiology Male Motor Activity - drug effects Motor Activity - physiology Movement Disorders - drug therapy Movement Disorders - pathology Movement Disorders - physiopathology Neuroprotective Agents - pharmacology Psychiatry Random Allocation Rats, Wistar Severity of Illness Index Treatment Outcome
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