Toxicokinetics of p-tert-octylphenol in female DA/Han rats after single i.v. and oral application

Female DA/Han rats were administered p-tert-octylphenol [OP; p-(1,1,3,3-tetramethylbutyl)-phenol], either intravenously (5 mg/kg body wt.) or orally by gavage (50 or 200 mg/kg body wt.). After i.v. administration the blood concentration-time curve of OP was fitted to a tri-exponential model, resulti...

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Veröffentlicht in:	Archives of toxicology 1999-07, Vol.73 (4-5), p.217-222
Hauptverfasser:	UPMEIER, A, DEGEN, G. H, SCHUHMACHER, U. S, CERTA, H, BOLT, H. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Biological and medical sciences Biological Availability Chemical and industrial products toxicology. Toxic occupational diseases Enterohepatic Circulation - physiology Female Infusions, Intravenous Medical sciences Phenols - blood Rats Time Factors Toxicology Various organic compounds
Online-Zugang:	Volltext
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