Gap junctional intercellular communication and connexin43 expression in human ovarian surface epithelial cells and ovarian carcinomas in vivo and in vitro

Gap junctional intercellular communication (GJIC) and the expression of gap junction proteins (connexins) are frequently decreased in neoplastic cells and have been increased by cAMP and retinoids. GJIC and connexin expression were investigated in early passage normal human ovarian surface epithelia...

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Veröffentlicht in:	Carcinogenesis (New York) 1999-07, Vol.20 (7), p.1369-1373
Hauptverfasser:	Hanna, Elizabeth A., Umhauer, Sandra, Roshong, Stacie L., Piechocki, Marie P., Fernstrom, Martha J., Fanning, James D., Ruch, Randall J.
Format:	Artikel
Sprache:	eng
Schlagworte:	2′-O-dibutyryladenosine 3 5′-cyclic monophosphate Adenocarcinoma - metabolism Adenocarcinoma - pathology all-trans-retinoic acid Animals ATRA Biological and medical sciences Blotting, Northern Blotting, Southern Blotting, Western Cell Communication - physiology Cells, Cultured Connexin 43 - biosynthesis connexin26 connexin32 connexin37 connexin40 connexin43 Cx26 Cx32 Cx37 Cx40 Cx43 DBcAMP Epithelial Cells - metabolism Female Female genital diseases Fluorescent Dyes gap junctional intercellular communication Gap Junctions - physiology GJIC Gynecology. Andrology. Obstetrics HOSE human ovarian surface epithelium Humans Immunohistochemistry Isoquinolines Medical sciences Mice Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology Ovary - cytology Ovary - metabolism PBS phosphate-buffered saline Rats Tumors
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