In silico binding affinity study of calcineurin inhibitors to calcineurin and its close associates

Calcineurin (CN) is a calcium regulated serine/threonine protein phosphatase. It is known to be inhibited by cyclosporin A (CsA), tacrolimus (FK506), endothall (ENDO), microcystin (MCYST), okadaic acid (OA) and trifluoperazine (TFP). CsA and FK506 are known inhibitors, which inhibit CN by binding to...

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Veröffentlicht in:	Indian journal of biotechnology 2013-04, Vol.12 (2), p.213-217
Hauptverfasser:	Harish, B M, Devaraju, K S, Gopi, A, Saraswathi, R, Anushree, Babu, R L, Sharma, S C
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Binding Binding energy Calcines Calcium Free energy Inhibition Inhibitors
Online-Zugang:	Volltext
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