Dietary supplementation with melatonin reduces levels of amyloid beta-peptides in the murine cerebral cortex

: Melatonin levels decrease with aging in mice. Dietary supplementation with melatonin has recently been shown to result in a significant rise in levels of endogenous melatonin in the serum and all other tissue samples tested. Herein, the effects of dietary melatonin on brain levels of nitric oxide...

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Veröffentlicht in:	Journal of pineal research 2004-05, Vol.36 (4), p.224-231
Hauptverfasser:	Lahiri, Debomoy K., Chen, Demao, Ge, Yuan-Wen, Bondy, Stephen C., Sharman, Edward H.
Format:	Artikel
Sprache:	eng
Schlagworte:	aging Aging - drug effects Aging - metabolism amyloid Amyloid beta-Peptides - metabolism Animals Antioxidants - pharmacology Biological and medical sciences Blotting, Western brain Cerebral Cortex - drug effects Cerebral Cortex - metabolism cognition diet Dietary Supplements Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology melatonin Melatonin - administration & dosage Melatonin - blood Mice mouse mRNA Neurodegenerative Diseases - metabolism Neurodegenerative Diseases - prevention & control Nitric Oxide Synthase - metabolism Peptide Fragments - metabolism synaptic protein Vertebrates: anatomy and physiology, studies on body, several organs or systems youth
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