A facile synthesis of 2H-indazoles under neat conditions and further transformation into aza-γ-carboline alkaloid analogues in a tandem one-pot fashion

We have described a facile, microwave-assisted, catalyst-free and solvent-free approach to 2H-indazoles and further developed a robust tandem one-pot metal-free strategy for C-C bond formation at the C-3 position of 2H-indazoles leading to a unique class of aza- gamma -carboline alkaloid analogues....

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Veröffentlicht in:RSC advances 2014-01, Vol.4 (65), p.34232-34236
Hauptverfasser: Vidyacharan, Shinde, Sagar, A., Chaitra, N. C., Sharada, Duddu S.
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container_end_page 34236
container_issue 65
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container_title RSC advances
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creator Vidyacharan, Shinde
Sagar, A.
Chaitra, N. C.
Sharada, Duddu S.
description We have described a facile, microwave-assisted, catalyst-free and solvent-free approach to 2H-indazoles and further developed a robust tandem one-pot metal-free strategy for C-C bond formation at the C-3 position of 2H-indazoles leading to a unique class of aza- gamma -carboline alkaloid analogues. This straightforward expedient synthesis constitutes an interesting alternative to the existing conventional transition metal catalyzed reactions.
doi_str_mv 10.1039/C4RA06838F
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source Royal Society Of Chemistry Journals 2008-
subjects Alkaloids
Bonding
Carbon-carbon composites
Catalysts
Strategy
Synthesis
Transformations
Transition metals
title A facile synthesis of 2H-indazoles under neat conditions and further transformation into aza-γ-carboline alkaloid analogues in a tandem one-pot fashion
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