Synthesis and steroid sulfatase inhibitory activities of N-alkanoyl tyramine phosphates and thiophosphates

A series of phosphate and thiophosphate analogs based on the frameworks of N -alkanoyl tyramines have been synthesized and biologically evaluated. Their binding modes have been modeled using docking techniques. The inhibitory effects of the synthesized compounds were tested on STS isolated from the...

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Veröffentlicht in:	RSC advances 2015-01, Vol.5 (41), p.32594-32603
Hauptverfasser:	Kozak, Witold, Daśko, Mateusz, Wołos, Agnieszka, Masłyk, Maciej, Kubiński, Konrad, Składanowski, Andrzej, Misiak, Majus, Rachon, Janusz, Demkowicz, Sebastian
Format:	Artikel
Sprache:	eng
Schlagworte:	Biotechnology Cancer Derivatives Dimethyl Inhibitors Phosphates Placenta Steroids
Online-Zugang:	Volltext
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