Reversible pH-responsive helical nanoribbons formed using camptothecin

Reversible pH-responsive helical nanoribbons formed using camptothecin

The natural antitumor drug camptothecin was found to self-assemble into helical nanoribbons in aqueous solution. The helical nanoribbons showed good reversible pH-responsiveness. The formation and disappearance of the helical nanoribbons can be tuned reversibly through changing the pH value of the s...

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Veröffentlicht in:RSC advances 2014-01, Vol.4 (80), p.42372-42375
Hauptverfasser: Ma, Mingfang, Xing, Pengyao, Xu, Shengguang, Li, Shangyang, Chu, Xiaoxiao, Hao, Aiyou
Format: Artikel
Sprache:eng
Schlagworte:
Aqueous solutions
Drugs
Formations
Helical
Nanostructure
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Zusammenfassung:The natural antitumor drug camptothecin was found to self-assemble into helical nanoribbons in aqueous solution. The helical nanoribbons showed good reversible pH-responsiveness. The formation and disappearance of the helical nanoribbons can be tuned reversibly through changing the pH value of the solution.
ISSN:2046-2069
2046-2069
DOI:10.1039/C4RA08225G