Who controls the ATP supply in cancer cells? Biochemistry lessons to understand cancer energy metabolism

•OxPhos can be the main ATP supplier in cancer cells under normoxia.•Glycolysis can be the main ATP supplier in cancer cells under hypoxia and low glucose.•Cancer glycolysis is mainly controlled by GLUT, HK, HPI and glycogenolysis.•Cancer OxPhos is controlled by the respiratory complexes and the cel...

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Veröffentlicht in:	The international journal of biochemistry & cell biology 2014-05, Vol.50, p.10-23
Hauptverfasser:	Moreno-Sánchez, Rafael, Marín-Hernández, Alvaro, Saavedra, Emma, Pardo, Juan P., Ralph, Stephen J., Rodríguez-Enríquez, Sara
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals ATP Biochemistry Biological Transport Cancer Cancer glutamine metabolism Chains Control equipment Energy Metabolism Glutamine - metabolism Glycolysis Humans Isocitrate dehydrogenase Metabolism Neoplasms - metabolism Oxidative Phosphorylation Pathways Warburg hypothesis
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