Efficient sodium bisulfite-catalyzed synthesis of benzothiazoles and their potential as ureases inhibitors

In this work we report the successful use of sodium bisulfite as catalyst for the synthesis of 19 benzothiazoles ( BZTs ) under microwave irradiation with yields from 80% to 100%. BZT-15 was the most active jack bean urease inhibitor exhibiting a mechanism of action typically of a mixed inhibitor. I...

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Veröffentlicht in:RSC advances 2015-01, Vol.5 (36), p.28814-28821
Hauptverfasser: Pereira Araujo, Débora, Santos Morais, Vinicius Stefano, de Fátima, Ângelo, Modolo, Luzia Valentina
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Sprache:eng
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