Sirt1 mediates the effects of a short-term high-fat diet on the heart

High-fat diet leads to development of cardiac dysfunction through molecular mechanisms poorly known. The aim of this study is to elucidate the early events in cardiac dysfunction caused by a high-fat diet, before massive alterations due to obesity and indirect mechanisms of heart damage take place....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of nutritional biochemistry 2015-11, Vol.26 (11), p.1328-1337
Hauptverfasser:	Villarroya, Joan, Redondo-Angulo, Ibon, Iglesias, Roser, Giralt, Marta, Villarroya, Francesc, Planavila, Anna
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cardiac dysfunction Cells, Cultured Diet, High-Fat - adverse effects Estrogen Receptor alpha - genetics Estrogen Receptor alpha - metabolism Gene Expression Regulation - drug effects Glucose Transporter Type 1 - genetics Glucose Transporter Type 1 - metabolism Glucose Transporter Type 4 - genetics Glucose Transporter Type 4 - metabolism Heart - drug effects Heart - physiology High-fat diet Male Metabolism Mice, Mutant Strains Myocytes, Cardiac - drug effects Myocytes, Cardiac - physiology NF-kappa B - metabolism PPAR alpha PPARα Rats, Sprague-Dawley Sirt1 Sirtuin 1 - genetics Sirtuin 1 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!