Unique activity associated with non‐insecticidal Bacillus thuringiensis parasporal inclusions: in vitro cell‐killing action on human cancer cells

Parasporal inclusion proteins from a total of 1744 Bacillus thuringiensis strains, consisting of 1700 Japanese isolates and 44 reference type strains of existing H serovars, were screened for cytocidal activity against human leukaemia T cells and haemolytic activity against sheep erythrocytes. Of 16...

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Veröffentlicht in:	Journal of applied microbiology 1999-03, Vol.86 (3), p.477-486
Hauptverfasser:	Mizuki, E., Ohba, M., Akao, T., Yamashita, S., Saitoh, H., Park, Y. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents Antineoplastic Agents - pharmacology Applied microbiology Bacillus thuringiensis Bacillus thuringiensis - chemistry Bacterial Proteins - analysis Bacterial Proteins - pharmacology Biological and medical sciences Bombyx - drug effects Chemotherapic agents Cockroaches - drug effects Diptera - drug effects Electrophoresis, Polyacrylamide Gel Erythrocytes - drug effects Fibroblasts - drug effects Fundamental and applied biological sciences. Psychology HeLa Cells Humans Insecticides - pharmacology Isoptera - drug effects Leukemia, T-Cell Lung Neoplasms Microbiology Orthoptera - drug effects Spores, Bacterial - chemistry
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