Intracranial Pressure Monitoring in Children With Severe Traumatic Brain Injury : National Trauma Data Bank–Based Review of Outcomes

IMPORTANCE The present study is the largest on the use and effect of intracranial pressure (ICP) monitoring in pediatric trauma patients. OBJECTIVE To determine the effect of ICP monitoring on survival in pediatric patients with severe head injuries using the National Trauma Data Bank. DESIGN, SETTI...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:JAMA surgery 2014-06, Vol.149 (6), p.544-548
Hauptverfasser: Alkhoury, Fuad, Kyriakides, Tassos C
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 548
container_issue 6
container_start_page 544
container_title JAMA surgery
container_volume 149
creator Alkhoury, Fuad
Kyriakides, Tassos C
description IMPORTANCE The present study is the largest on the use and effect of intracranial pressure (ICP) monitoring in pediatric trauma patients. OBJECTIVE To determine the effect of ICP monitoring on survival in pediatric patients with severe head injuries using the National Trauma Data Bank. DESIGN, SETTING, AND PARTICIPANTS The National Trauma Data Bank was queried (version 6.2, 2001-2006) for information on patients younger than 17 years admitted to an intensive care unit with blunt traumatic brain injury (TBI), Injury Severity Score (ISS) greater than 9, and Glasgow Coma Scale (GCS) score less than 9. Patients with incomplete medical records and those with intensive care unit length of stay of less than 24 hours were excluded from the study. MAIN OUTCOMES AND MEASURES Parametric comparisons (t tests and χ2 as appropriate) were performed to compare patients who received ICP monitoring with those who did not. Stepwise logistic regression methods were used to assess whether ICP monitoring in the presence of other variables (age, sex, ISS, Revised Trauma Score, and GCS score) was associated with survival. RESULTS Monitoring of ICP was performed in only 7.7% of patients who met the monitoring criteria recommended by the Brain Trauma Foundation. There were no significant differences in age, sex, or GCS score. After adjustment for admission GCS score, age group, sex, Revised Trauma Score, and injury ISS, ICP monitoring was associated with a reduction in mortality only for patients with a GCS score of 3 (odds ratio, 0.64; 95% CI, 0.43-1.00). Comparison between the 2 groups showed that the ICP monitoring group had a longer hospital length of stay (21.0 days vs 10.4 days; P 
doi_str_mv 10.1001/jamasurg.2013.4329
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1728675079</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ama_id>1864180</ama_id><sourcerecordid>1728675079</sourcerecordid><originalsourceid>FETCH-LOGICAL-a273t-bdba589699de36c2bee68e070dbe04b33ad6148975b1dc51ab87b92bb08282a23</originalsourceid><addsrcrecordid>eNpFkctO3DAUhi3UChDwAiyQl93M1JfEsdkxA5SRoKCWqsvoODkDHhIH7ATEjhUvwBvyJHg0XM7GR9b3f4vzE7LL2Zgzxn8uoIU4hKuxYFyOMynMGtkUXOmREkp8-9zzbIPsxLhgaTRjmTTrZENkhTaZUJvkeeb7AFUA76ChFwFjkiI967zru-D8FXWeTq9dUwf09L_rr-lfvMeEXAYYWuhdRScBEjTziyE80n36O312PtlWBD2EHugE_M3r08sEItb0D947fKDdnJ4PfdW1GLfJ9zk0EXfe3y3y7_jocnoyOj3_NZsenI5AFLIf2dpCro0ypkapKmERlUZWsNoiy6yUUCueaVPkltdVzsHqwhphLdNCCxByi_xYeW9Ddzdg7MvWxQqbBjx2Qyx5IbQqclaYhIoVWoUuxoDz8ja4FsJjyVm5rKD8qKBcVlAuK0ihvXf_YFusPyMfB0_A7gpI2S-hVhnXTL4Bho-Oyw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1728675079</pqid></control><display><type>article</type><title>Intracranial Pressure Monitoring in Children With Severe Traumatic Brain Injury : National Trauma Data Bank–Based Review of Outcomes</title><source>MEDLINE</source><source>American Medical Association Journals</source><creator>Alkhoury, Fuad ; Kyriakides, Tassos C</creator><creatorcontrib>Alkhoury, Fuad ; Kyriakides, Tassos C</creatorcontrib><description>IMPORTANCE The present study is the largest on the use and effect of intracranial pressure (ICP) monitoring in pediatric trauma patients. OBJECTIVE To determine the effect of ICP monitoring on survival in pediatric patients with severe head injuries using the National Trauma Data Bank. DESIGN, SETTING, AND PARTICIPANTS The National Trauma Data Bank was queried (version 6.2, 2001-2006) for information on patients younger than 17 years admitted to an intensive care unit with blunt traumatic brain injury (TBI), Injury Severity Score (ISS) greater than 9, and Glasgow Coma Scale (GCS) score less than 9. Patients with incomplete medical records and those with intensive care unit length of stay of less than 24 hours were excluded from the study. MAIN OUTCOMES AND MEASURES Parametric comparisons (t tests and χ2 as appropriate) were performed to compare patients who received ICP monitoring with those who did not. Stepwise logistic regression methods were used to assess whether ICP monitoring in the presence of other variables (age, sex, ISS, Revised Trauma Score, and GCS score) was associated with survival. RESULTS Monitoring of ICP was performed in only 7.7% of patients who met the monitoring criteria recommended by the Brain Trauma Foundation. There were no significant differences in age, sex, or GCS score. After adjustment for admission GCS score, age group, sex, Revised Trauma Score, and injury ISS, ICP monitoring was associated with a reduction in mortality only for patients with a GCS score of 3 (odds ratio, 0.64; 95% CI, 0.43-1.00). Comparison between the 2 groups showed that the ICP monitoring group had a longer hospital length of stay (21.0 days vs 10.4 days; P &lt; .001), longer intensive care unit stay (12.6 vs 6.3 days; P &lt; .001), and more ventilator days (9.2 vs 4.7; P &lt; .001). CONCLUSIONS AND RELEVANCE Despite current Brain Trauma Foundation guidelines, ICP monitoring is used infrequently in the pediatric population. The data suggest that there is a small, yet statistically significant, survival advantage in patients who have ICP monitors and a GCS score of 3. However, all patients with ICP monitors experienced longer hospital length of stay, longer intensive care unit stay, and more ventilator days compared with those without ICP monitors. A prospective observational study would be helpful to accurately define the population for whom ICP monitoring is advantageous.</description><identifier>ISSN: 2168-6254</identifier><identifier>EISSN: 2168-6262</identifier><identifier>DOI: 10.1001/jamasurg.2013.4329</identifier><identifier>PMID: 24789426</identifier><language>eng</language><publisher>United States: American Medical Association</publisher><subject>Brain Injuries - mortality ; Brain Injuries - physiopathology ; Child ; Female ; Glasgow Coma Scale ; Hospital Charges ; Humans ; Injury Severity Score ; Intensive Care Units ; Intracranial Pressure ; Length of Stay - statistics &amp; numerical data ; Male ; Monitoring, Physiologic - methods ; Respiration, Artificial - statistics &amp; numerical data ; Survival Rate</subject><ispartof>JAMA surgery, 2014-06, Vol.149 (6), p.544-548</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jamanetwork.com/journals/jamasurgery/articlepdf/10.1001/jamasurg.2013.4329$$EPDF$$P50$$Gama$$H</linktopdf><linktohtml>$$Uhttps://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2013.4329$$EHTML$$P50$$Gama$$H</linktohtml><link.rule.ids>64,314,776,780,3327,27901,27902,76231,76234</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24789426$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Alkhoury, Fuad</creatorcontrib><creatorcontrib>Kyriakides, Tassos C</creatorcontrib><title>Intracranial Pressure Monitoring in Children With Severe Traumatic Brain Injury : National Trauma Data Bank–Based Review of Outcomes</title><title>JAMA surgery</title><addtitle>JAMA Surg</addtitle><description>IMPORTANCE The present study is the largest on the use and effect of intracranial pressure (ICP) monitoring in pediatric trauma patients. OBJECTIVE To determine the effect of ICP monitoring on survival in pediatric patients with severe head injuries using the National Trauma Data Bank. DESIGN, SETTING, AND PARTICIPANTS The National Trauma Data Bank was queried (version 6.2, 2001-2006) for information on patients younger than 17 years admitted to an intensive care unit with blunt traumatic brain injury (TBI), Injury Severity Score (ISS) greater than 9, and Glasgow Coma Scale (GCS) score less than 9. Patients with incomplete medical records and those with intensive care unit length of stay of less than 24 hours were excluded from the study. MAIN OUTCOMES AND MEASURES Parametric comparisons (t tests and χ2 as appropriate) were performed to compare patients who received ICP monitoring with those who did not. Stepwise logistic regression methods were used to assess whether ICP monitoring in the presence of other variables (age, sex, ISS, Revised Trauma Score, and GCS score) was associated with survival. RESULTS Monitoring of ICP was performed in only 7.7% of patients who met the monitoring criteria recommended by the Brain Trauma Foundation. There were no significant differences in age, sex, or GCS score. After adjustment for admission GCS score, age group, sex, Revised Trauma Score, and injury ISS, ICP monitoring was associated with a reduction in mortality only for patients with a GCS score of 3 (odds ratio, 0.64; 95% CI, 0.43-1.00). Comparison between the 2 groups showed that the ICP monitoring group had a longer hospital length of stay (21.0 days vs 10.4 days; P &lt; .001), longer intensive care unit stay (12.6 vs 6.3 days; P &lt; .001), and more ventilator days (9.2 vs 4.7; P &lt; .001). CONCLUSIONS AND RELEVANCE Despite current Brain Trauma Foundation guidelines, ICP monitoring is used infrequently in the pediatric population. The data suggest that there is a small, yet statistically significant, survival advantage in patients who have ICP monitors and a GCS score of 3. However, all patients with ICP monitors experienced longer hospital length of stay, longer intensive care unit stay, and more ventilator days compared with those without ICP monitors. A prospective observational study would be helpful to accurately define the population for whom ICP monitoring is advantageous.</description><subject>Brain Injuries - mortality</subject><subject>Brain Injuries - physiopathology</subject><subject>Child</subject><subject>Female</subject><subject>Glasgow Coma Scale</subject><subject>Hospital Charges</subject><subject>Humans</subject><subject>Injury Severity Score</subject><subject>Intensive Care Units</subject><subject>Intracranial Pressure</subject><subject>Length of Stay - statistics &amp; numerical data</subject><subject>Male</subject><subject>Monitoring, Physiologic - methods</subject><subject>Respiration, Artificial - statistics &amp; numerical data</subject><subject>Survival Rate</subject><issn>2168-6254</issn><issn>2168-6262</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkctO3DAUhi3UChDwAiyQl93M1JfEsdkxA5SRoKCWqsvoODkDHhIH7ATEjhUvwBvyJHg0XM7GR9b3f4vzE7LL2Zgzxn8uoIU4hKuxYFyOMynMGtkUXOmREkp8-9zzbIPsxLhgaTRjmTTrZENkhTaZUJvkeeb7AFUA76ChFwFjkiI967zru-D8FXWeTq9dUwf09L_rr-lfvMeEXAYYWuhdRScBEjTziyE80n36O312PtlWBD2EHugE_M3r08sEItb0D947fKDdnJ4PfdW1GLfJ9zk0EXfe3y3y7_jocnoyOj3_NZsenI5AFLIf2dpCro0ypkapKmERlUZWsNoiy6yUUCueaVPkltdVzsHqwhphLdNCCxByi_xYeW9Ddzdg7MvWxQqbBjx2Qyx5IbQqclaYhIoVWoUuxoDz8ja4FsJjyVm5rKD8qKBcVlAuK0ihvXf_YFusPyMfB0_A7gpI2S-hVhnXTL4Bho-Oyw</recordid><startdate>20140601</startdate><enddate>20140601</enddate><creator>Alkhoury, Fuad</creator><creator>Kyriakides, Tassos C</creator><general>American Medical Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140601</creationdate><title>Intracranial Pressure Monitoring in Children With Severe Traumatic Brain Injury : National Trauma Data Bank–Based Review of Outcomes</title><author>Alkhoury, Fuad ; Kyriakides, Tassos C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a273t-bdba589699de36c2bee68e070dbe04b33ad6148975b1dc51ab87b92bb08282a23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Brain Injuries - mortality</topic><topic>Brain Injuries - physiopathology</topic><topic>Child</topic><topic>Female</topic><topic>Glasgow Coma Scale</topic><topic>Hospital Charges</topic><topic>Humans</topic><topic>Injury Severity Score</topic><topic>Intensive Care Units</topic><topic>Intracranial Pressure</topic><topic>Length of Stay - statistics &amp; numerical data</topic><topic>Male</topic><topic>Monitoring, Physiologic - methods</topic><topic>Respiration, Artificial - statistics &amp; numerical data</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alkhoury, Fuad</creatorcontrib><creatorcontrib>Kyriakides, Tassos C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>JAMA surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alkhoury, Fuad</au><au>Kyriakides, Tassos C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intracranial Pressure Monitoring in Children With Severe Traumatic Brain Injury : National Trauma Data Bank–Based Review of Outcomes</atitle><jtitle>JAMA surgery</jtitle><addtitle>JAMA Surg</addtitle><date>2014-06-01</date><risdate>2014</risdate><volume>149</volume><issue>6</issue><spage>544</spage><epage>548</epage><pages>544-548</pages><issn>2168-6254</issn><eissn>2168-6262</eissn><abstract>IMPORTANCE The present study is the largest on the use and effect of intracranial pressure (ICP) monitoring in pediatric trauma patients. OBJECTIVE To determine the effect of ICP monitoring on survival in pediatric patients with severe head injuries using the National Trauma Data Bank. DESIGN, SETTING, AND PARTICIPANTS The National Trauma Data Bank was queried (version 6.2, 2001-2006) for information on patients younger than 17 years admitted to an intensive care unit with blunt traumatic brain injury (TBI), Injury Severity Score (ISS) greater than 9, and Glasgow Coma Scale (GCS) score less than 9. Patients with incomplete medical records and those with intensive care unit length of stay of less than 24 hours were excluded from the study. MAIN OUTCOMES AND MEASURES Parametric comparisons (t tests and χ2 as appropriate) were performed to compare patients who received ICP monitoring with those who did not. Stepwise logistic regression methods were used to assess whether ICP monitoring in the presence of other variables (age, sex, ISS, Revised Trauma Score, and GCS score) was associated with survival. RESULTS Monitoring of ICP was performed in only 7.7% of patients who met the monitoring criteria recommended by the Brain Trauma Foundation. There were no significant differences in age, sex, or GCS score. After adjustment for admission GCS score, age group, sex, Revised Trauma Score, and injury ISS, ICP monitoring was associated with a reduction in mortality only for patients with a GCS score of 3 (odds ratio, 0.64; 95% CI, 0.43-1.00). Comparison between the 2 groups showed that the ICP monitoring group had a longer hospital length of stay (21.0 days vs 10.4 days; P &lt; .001), longer intensive care unit stay (12.6 vs 6.3 days; P &lt; .001), and more ventilator days (9.2 vs 4.7; P &lt; .001). CONCLUSIONS AND RELEVANCE Despite current Brain Trauma Foundation guidelines, ICP monitoring is used infrequently in the pediatric population. The data suggest that there is a small, yet statistically significant, survival advantage in patients who have ICP monitors and a GCS score of 3. However, all patients with ICP monitors experienced longer hospital length of stay, longer intensive care unit stay, and more ventilator days compared with those without ICP monitors. A prospective observational study would be helpful to accurately define the population for whom ICP monitoring is advantageous.</abstract><cop>United States</cop><pub>American Medical Association</pub><pmid>24789426</pmid><doi>10.1001/jamasurg.2013.4329</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 2168-6254
ispartof JAMA surgery, 2014-06, Vol.149 (6), p.544-548
issn 2168-6254
2168-6262
language eng
recordid cdi_proquest_miscellaneous_1728675079
source MEDLINE; American Medical Association Journals
subjects Brain Injuries - mortality
Brain Injuries - physiopathology
Child
Female
Glasgow Coma Scale
Hospital Charges
Humans
Injury Severity Score
Intensive Care Units
Intracranial Pressure
Length of Stay - statistics & numerical data
Male
Monitoring, Physiologic - methods
Respiration, Artificial - statistics & numerical data
Survival Rate
title Intracranial Pressure Monitoring in Children With Severe Traumatic Brain Injury : National Trauma Data Bank–Based Review of Outcomes
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-10T03%3A59%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Intracranial%20Pressure%20Monitoring%20in%20Children%20With%20Severe%20Traumatic%20Brain%20Injury%20:%20National%20Trauma%20Data%20Bank%E2%80%93Based%20Review%20of%20Outcomes&rft.jtitle=JAMA%20surgery&rft.au=Alkhoury,%20Fuad&rft.date=2014-06-01&rft.volume=149&rft.issue=6&rft.spage=544&rft.epage=548&rft.pages=544-548&rft.issn=2168-6254&rft.eissn=2168-6262&rft_id=info:doi/10.1001/jamasurg.2013.4329&rft_dat=%3Cproquest_cross%3E1728675079%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1728675079&rft_id=info:pmid/24789426&rft_ama_id=1864180&rfr_iscdi=true