Choosing the right chondrocyte cell line: Focus on nitric oxide

ABSTRACT Nitric oxide (NO) has been considered a catabolic factor that contributes to OA pathology by inducing chondrocytes apoptosis, matrix metalloproteinases synthesis, and pro‐inflammatory cytokines expression. Thus, the research on NO regulation in chondrocytes represents a relevant field which...

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Veröffentlicht in:	Journal of orthopaedic research 2015-12, Vol.33 (12), p.1784-1788
Hauptverfasser:	Santoro, Anna, Conde, Javier, Scotece, Morena, Abella, Vanessa, López, Verónica, Pino, Jesús, Gómez, Rodolfo, Gómez-Reino, Juan Jesús, Gualillo, Oreste
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthroplasty, Replacement Blotting, Western Cartilage - pathology Cell Culture Techniques Cell Line chondrocyte cell lines Chondrocytes - cytology Colorimetry cytokines Endotoxins - chemistry Humans Inflammation Interleukin-1alpha - metabolism Lipopolysaccharides - chemistry Mice nitric oxide Nitric Oxide - chemistry Nitric Oxide Synthase Type II - metabolism Osteoarthritis - physiopathology Research Design
Online-Zugang:	Volltext
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