A Simple Novel Technique to Estimate Tacrolimus Dosages During the Early Post Kidney Transplantation Period

Abstract Background Tacrolimus pharmacokinetics prediction by CYP3A5 genotyping is not available in many Asian resource-limited settings. Therefore, an alternative technique is needed to estimate the dose of tacrolimus perioperatively. The 12-hour level after the first dose (C12-0) is an alternative...

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Veröffentlicht in:	Transplantation proceedings 2015-10, Vol.47 (8), p.2433-2438
Hauptverfasser:	Townamchai, N, Chancharoenthana, W, Vadcharavivad, S, Chariyavilaskul, P, Pongpirul, K, Leelahavanichkul, A, Watanatorn, S, Avihingsanon, Y, Praditpornsilpa, K, Srisawat, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Asian Continental Ancestry Group - genetics Cytochrome P-450 CYP3A - genetics Dose-Response Relationship, Drug Female Genotype Humans Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - pharmacokinetics Kidney Failure, Chronic - genetics Kidney Failure, Chronic - metabolism Kidney Failure, Chronic - surgery Kidney Transplantation Male Middle Aged Prospective Studies Surgery Tacrolimus - administration & dosage Tacrolimus - pharmacokinetics
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