Identification of a molecular target of kurahyne, an apoptosis-inducing lipopeptide from marine cyanobacterial assemblages

[Display omitted] In 2014, we isolated kurahyne, an acetylene-containing lipopeptide, from a marine cyanobacterial assemblage of Lyngbya sp. Kurahyne exhibited growth-inhibitory activity against human cancer cells, and induced apoptosis in HeLa cells. However, its mode of action is not yet clear. To...

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Veröffentlicht in:Bioorganic & medicinal chemistry letters 2015-11, Vol.25 (22), p.5295-5298
Hauptverfasser: Iwasaki, Arihiro, Ohno, Osamu, Katsuyama, Shun, Morita, Maho, Sasazawa, Yukiko, Dan, Shingo, Simizu, Siro, Yamori, Takao, Suenaga, Kiyotake
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Sprache:eng
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