Orthogonal bioorthogonal chemistries

•Mutually orthogonal bioorthogonal reactions are described.•Current challenges in compatible reaction development are outlined.•Strategies to identify and generate orthogonal reactions are presented.•Recent applications of orthogonal bioorthogonal reactions in cellular imaging and macromolecular ass...

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Veröffentlicht in:	Current opinion in chemical biology 2015-10, Vol.28, p.141-149
Hauptverfasser:	Patterson, David M, Prescher, Jennifer A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes - chemistry Animals Azides - chemistry Biochemistry - methods Humans Models, Molecular Molecular Imaging - methods Proteins - analysis Proteins - metabolism
Online-Zugang:	Volltext
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