MicoRNA-451 is a novel tumor suppressor via targeting c-myc in head and neck squamous cell carcinomas

Head and neck squamous cell carcinoma (HNSCC) represents as a common malignancy with increasing incidence in the worldwide. The fact of its poor survival rate urgently requires developing efficient predictive biomarkers for clinical use. MicroRNAs (miRNAs) recently represent as a novel direction for...

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Veröffentlicht in:	Journal of cancer research and therapeutics 2015-10, Vol.11 Suppl 2 (6), p.C216-C221
Hauptverfasser:	Wang, Huimin, Zhang, Guozheng, Wu, Zhiyan, Lu, Baocai, Yuan, Dongjie, Li, Xiao, Lu, Zhenmin
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Biomarkers Biomarkers, Tumor Bladder cancer Bone cancer Breast cancer Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - surgery Care and treatment Cell growth Cell Line Cell Proliferation - genetics Gene Expression Gene Expression Regulation, Neoplastic Genes, Tumor Suppressor Genetic aspects Head and neck cancer Head and Neck Neoplasms - genetics Head and Neck Neoplasms - pathology Head and Neck Neoplasms - surgery Health aspects Humans Medical prognosis Metastasis MicroRNA MicroRNAs MicroRNAs - chemistry MicroRNAs - genetics Polymerase chain reaction Proto-Oncogene Proteins c-myc - chemistry Proto-Oncogene Proteins c-myc - genetics RNA Interference RNA, Messenger - chemistry RNA, Messenger - genetics Rodents Squamous Cell Carcinoma of Head and Neck
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