Ratiometric Biosensor for Aggregation-Induced Emission-Guided Precise Photodynamic Therapy

Photodynamic therapy faces the barrier of choosing the appropriate irradiation region and time. In this paper, a matrix metalloproteinase-2 (MMP-2) responsive ratiometric biosensor was designed and synthesized for aggregation-induced emission (AIE)-guided precise photodynamic therapy. It was found t...

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Veröffentlicht in:	ACS nano 2015-10, Vol.9 (10), p.10268-10277
Hauptverfasser:	Han, Kai, Wang, Shi-Bo, Lei, Qi, Zhu, Jing-Yi, Zhang, Xian-Zheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biosensing Techniques - methods Cell Line, Tumor Humans Matrix Metalloproteinase 2 - analysis Matrix Metalloproteinase 2 - metabolism Mice Neoplasms - diagnosis Neoplasms - drug therapy Neoplasms - pathology Optical Imaging - methods Photochemotherapy - methods Photosensitizing Agents - chemistry Photosensitizing Agents - therapeutic use Precision Medicine - methods Protoporphyrins - chemistry Protoporphyrins - therapeutic use
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