Night-shift work increases morbidity of breast cancer and all-cause mortality: a meta-analysis of 16 prospective cohort studies

Highlights • This meta-analysis included 16 prospective cohort studies. • A positive dose–effect relationship was found between night-shift work and incident breast tumors. • Rotating night-shift work enhances morbidity of breast cancer by 8.9%. • Night-shift work is associated with a 2.7% increase...

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Veröffentlicht in:	Sleep medicine 2015-11, Vol.16 (11), p.1381-1387
Hauptverfasser:	Lin, Xiaoti, Chen, Weiyu, Wei, Fengqin, Ying, Mingang, Wei, Weidong, Xie, Xiaoming
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Breast cancer Breast Neoplasms - epidemiology Breast Neoplasms - etiology Cardiovascular Diseases - mortality Circadian Rhythm - physiology Female Humans Meta-analysis Middle Aged Morbidity Mortality Neoplasms - mortality Neurology Night-shift work Prospective Studies Prospective study Risk Factors Sleep Medicine Work Schedule Tolerance - physiology Work Schedule Tolerance - psychology Young Adult
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Zusammenfassung:	Highlights • This meta-analysis included 16 prospective cohort studies. • A positive dose–effect relationship was found between night-shift work and incident breast tumors. • Rotating night-shift work enhances morbidity of breast cancer by 8.9%. • Night-shift work is associated with a 2.7% increase in cardiovascular death.
ISSN:	1389-9457 1878-5506
DOI:	10.1016/j.sleep.2015.02.543