Insights into molecular profiles and genomic evolution of an IRAK4 homolog from rock bream (Oplegnathus fasciatus): Immunogen- and pathogen-induced transcriptional expression

As a pivotal signaling mediator of toll-like receptor (TLR) and interleukin (IL)-1 receptor (IL-1R) signaling cascades, the IL-1R-associated kinase 4 (IRAK4) is engaged in the activation of host immunity. This study investigates the molecular and expressional profiles of an IRAK4-like homolog from O...

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Veröffentlicht in:	Fish & shellfish immunology 2015-04, Vol.43 (2), p.436-448
Hauptverfasser:	Umasuthan, Navaneethaiyer, Bathige, S.D.N.K., Whang, Ilson, Lim, Bong-Soo, Choi, Cheol Young, Lee, Jehee
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Bass - genetics Bass - immunology DNA, Complementary - genetics DNA, Complementary - metabolism Edwardsiella tarda Edwardsiella tarda - physiology Fish Proteins - chemistry Fish Proteins - genetics Fish Proteins - metabolism Flagellin (FLA) Gene Expression Regulation Genome Genomic evolution IL-1R-associated kinase 4 (IRAK4) Immune responses Immunity, Innate Interleukin-1 Receptor-Associated Kinases - chemistry Interleukin-1 Receptor-Associated Kinases - genetics Interleukin-1 Receptor-Associated Kinases - metabolism Iridoviridae Iridovirus Iridovirus - physiology Lipopolysaccharides - administration & dosage Molecular Sequence Data Oplegnathus fasciatus Organ Specificity Phylogeny Poly I-C - administration & dosage Promoter Regions, Genetic Putative promoter Streptococcus - physiology Streptococcus iniae Teleostei
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