Improved antibacterial phototoxicity of a neutral porphyrin in natural deep eutectic solvents

•The neutral porphyrin THPP was soluble in selected natural deep eutectic solvents.•THPP remained soluble even upon 200-fold dilution in water.•THPP was highly phototoxic towards bacteria at pM concentrations.•The formulation is crucial for optimal phototoxicity of neutral porphyrins. Neutral porphy...

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Veröffentlicht in:	Journal of photochemistry and photobiology. B, Biology Biology, 2015-07, Vol.148, p.188-196
Hauptverfasser:	Wikene, Kristine Opsvik, Bruzell, Ellen, Tønnesen, Hanne Hjorth
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Enterococcus faecalis Enterococcus faecalis - drug effects Enterococcus faecalis - radiation effects Escherichia coli Escherichia coli - drug effects Escherichia coli - radiation effects Hydrophobic and Hydrophilic Interactions Light Photosensitizing Agents - chemistry Photosensitizing Agents - toxicity Propiophenones - chemistry Propiophenones - toxicity Solubility Solvents - chemistry
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